Corynebacterium glutamicum, Escherichia coli, and Saccharomyces cerevisiae in particular,
have become established as important industrial workhorses in biotechnology. Recent years …

Along with the development of metabolic engineering and synthetic biology tools, various
microbes are being used to produce aromatic chemicals. In microbes, aromatics are mainly …

Corynebacterium glutamicum, a well-studied industrial model microorganism, has garnered
widespread attention due to its ability for producing amino acids with a long history. In recent …

Hyaluronic acid (HA) is a polysaccharide used in many industries such as medicine,
surgery, cosmetics, and food. To avoid potential pathogenicity caused by its native producer …

Background Styrene is a versatile commodity petrochemical used as a monomer building-
block for the synthesis of many useful polymers. Although achievements have been made …

Background 2-Phenylethanol is a specific aromatic alcohol with a rose-like smell, which has
been widely used in the cosmetic and food industries. At present, 2-phenylethanol is mainly …

Continuous directed evolution (CDE) is a powerful tool for enzyme engineering due to the
depth and scale of evolutionary search that it enables. If suitably controlled and calibrated …

Oligosaccharides and polysaccharides constitute the principal components of
carbohydrates, which are important biomacromolecules that demonstrate considerable …

Corynebacterium glutamicum is an important industrial microorganism, but the availability of
tools for its genetic modification has lagged compared to other model microorganisms such …

Aromatic compounds such as l-phenylalanine, 2-phenylethanol and trans-cinnamate are
aromatic compounds of industrial interest. Current trends support replacement of chemical …