Environmental and health effects of the herbicide glyphosate

AHC Van Bruggen, MM He, K Shin, V Mai… - Science of the total …, 2018 - Elsevier
The herbicide glyphosate, N-(phosphonomethyl) glycine, has been used extensively in the
past 40 years, under the assumption that side effects were minimal. However, in recent …

Glyphosate: uses other than in glyphosate-resistant crops, mode of action, degradation in plants, and effects on non-target plants and agricultural microbes

SO Duke - Reviews of Environmental Contamination and …, 2021 - Springer
Glyphosate is the most used herbicide globally. It is a unique non-selective herbicide with a
mode of action that is ideal for vegetation management in both agricultural and non …

[HTML][HTML] Indirect effects of the herbicide glyphosate on plant, animal and human health through its effects on microbial communities

AHC Van Bruggen, MR Finckh, M He… - Frontiers in …, 2021 - frontiersin.org
The herbicide glyphosate interferes with the shikimate pathway in plants and in major
groups of microorganisms impeding the production of aromatic amino acids. Glyphosate …

Revisiting the shikimate pathway and highlighting their enzyme inhibitors

AM Almeida, R Marchiosi, J Abrahão… - Phytochemistry …, 2024 - Springer
Absent in animals and with only seven enzymatic reactions toward the synthesis of
chorismate and aromatic amino acids, the shikimate pathway is a crucial target for …

Structural basis of glyphosate resistance resulting from the double mutation Thr97→ Ile and Pro101→ Ser in 5-enolpyruvylshikimate-3-phosphate synthase from …

T Funke, Y Yang, H Han, M Healy-Fried… - Journal of Biological …, 2009 - ASBMB
The shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) is
the target of the broad spectrum herbicide glyphosate. The genetic engineering of EPSPS …

Structural genomics for drug design against the pathogen Coxiella burnetii

MC Franklin, J Cheung, MJ Rudolph… - Proteins: Structure …, 2015 - Wiley Online Library
Coxiella burnetii is a highly infectious bacterium and potential agent of bioterrorism.
However, it has not been studied as extensively as other biological agents, and very few of …

Mycobacterium tuberculosis Shikimate Pathway Enzymes as Targets for the Rational Design of Anti-Tuberculosis Drugs

JES Nunes, MA Duque, TF de Freitas, L Galina… - Molecules, 2020 - mdpi.com
Roughly a third of the world's population is estimated to have latent Mycobacterium
tuberculosis infection, being at risk of developing active tuberculosis (TB) during their …

Glyphosate-based herbicide exposure: effects on gill microbiota of rainbow trout (Oncorhynchus mykiss) and the aquatic bacterial ecosystem

L Bellec, J Le Du-Carré, F Almeras… - FEMS Microbiology …, 2022 - academic.oup.com
The herbicide glyphosate has been widely used in the past 40 years, under the assumption
that side effects were minimal. In recent years, its impact on microbial compositions and …

Glyphosate-based herbicide affects the composition of microbes associated with Colorado potato beetle (Leptinotarsa decemlineata)

C Gomez-Gallego, MJ Rainio… - FEMS Microbiology …, 2020 - academic.oup.com
Here, we examined whether glyphosate affects the microbiota of herbivores feeding on non-
target plants. Colorado potato beetles (Leptinotarsa decemlineata) were reared on potato …

Glyphosate Bioremediation through the Sarcosine Oxidase Pathway Mediated by Lysinibacillus sphaericus in Soils Cultivated with Potatoes

M Pérez Rodríguez, C Melo, E Jiménez, J Dussán - Agriculture, 2019 - mdpi.com
Glyphosate-based herbicides (GBH) use has increased drastically over the last decade. This
is true especially for potato crops due to their fast harvest cycle and high market demand. In …