ROS: basic concepts, sources, cellular signaling, and its implications in aging pathways

AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

Involvement of inflammation and its resolution in disease and therapeutics

S Alfaro, V Acuña, R Ceriani, MF Cavieres… - International Journal of …, 2022 - mdpi.com
Inflammation plays a critical role in the response to and survival from injuries and/or
infections. It occurs in two phases: initiation and resolution; however, when these events do …

Poly-L-lactic acid fillers improved dermal collagen synthesis by modulating M2 macrophage polarization in aged animal skin

S Oh, JH Lee, HM Kim, S Batsukh, MJ Sung, TH Lim… - Cells, 2023 - mdpi.com
Poly-L-lactic acid (PLLA) fillers correct cutaneous volume loss by stimulating fibroblasts to
synthesize collagen and by augmenting the volume. PLLA triggers the macrophage-induced …

Poly-D, L-lactic acid stimulates angiogenesis and collagen synthesis in aged animal skin

S Oh, SB Seo, G Kim, S Batsukh, KH Son… - International Journal of …, 2023 - mdpi.com
Angiogenesis promotes rejuvenation in multiple organs, including the skin. Heat shock
protein 90 (HSP90), hypoxia-inducible factor-1 alpha (HIF-1α), and vascular endothelial …

Poly-D, L-lactic acid filler increases extracellular matrix by modulating macrophages and adipose-derived stem cells in aged animal skin

S Oh, SB Seo, G Kim, S Batsukh, CH Park, KH Son… - Antioxidants, 2023 - mdpi.com
Poly-D, L-lactic acid (PDLLA) filler corrects soft tissue volume loss by increasing collagen
synthesis in the dermis; however, the mechanism is not fully understood. Adipose-derived …

[HTML][HTML] Resolvin E1 attenuates doxorubicin-induced cardiac fibroblast senescence: A key role for IL-1β

JA Espitia-Corredor, L Shamoon… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Cardiac fibroblasts (CFs) undergo senescence in reaction to different stressors, leading to a
poor prognosis of cardiac disease. Doxorubicin (Doxo) is an antineoplastic drug with strong …

Oxidative stress and cell senescence process

R Faraonio - Antioxidants, 2022 - mdpi.com
Oxidative stress due to excessive amounts of reactive oxygen species (ROS) and reactive
nitrogen species (RNS) plays a leading role in damages to macromolecules and, as such, it …

[HTML][HTML] Snail promotes cancer cell proliferation via its interaction with the BIRC3

SB Rho, HJ Byun, BR Kim, CH Lee - Biomolecules & Therapeutics, 2022 - ncbi.nlm.nih.gov
Snail is implicated in tumour growth and metastasis and is up-regulated in various human
tumours. Although the role of Snails in epithelial-mesenchymal transition, which is …

Restoration of epigenetic impairment in the skeletal muscle and chronic inflammation resolution as a therapeutic approach in sarcopenia

G Livshits, A Kalinkovich - Ageing Research Reviews, 2024 - Elsevier
Sarcopenia is an age-associated loss of skeletal muscle mass, strength, and function,
accompanied by severe adverse health outcomes, such as falls and fractures, functional …

3'UTR of SARS-CoV-2 spike gene hijack host miR-296 or miR-520h to disturb cell proliferation and cytokine signaling

J Yuan, Z Feng, Q Wang, L Han, S Guan, L Liu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has becoming globally
public health threat. Recently studies were focus on SARS-CoV-2 RNA to design vaccine …