Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …

Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate
direct intercellular communication, a critical feature for the development, function, and …

Of the 21 members of the connexin family, 4 (Cx37, Cx40, Cx43, and Cx45) are expressed in
the endothelium and/or smooth muscle of intact blood vessels to a variable and dynamically …

Connexins and integrins, the two structurally and functionally distinct families of
transmembrane proteins, have been shown to be inter-connected by various modes of cross …

Increased oxidative stress contributes to cataract formation during aging. Anterior epithelial
cells are a frontline antioxidant defense system with powerful capacities to maintain redox …

Redox status is a key determinant in the fate of β-cell. These cells are not primarily
detoxifying and thus do not possess extensive antioxidant defense machinery. However …

Simple Summary Connexins are proteins which comprise gap junctions in cells. These
junctions can directly connect neighboring cells and the cell interior with the extracellular …

Vascular endothelial cells, as well as smooth muscle cells, show heterogeneity with regard
to their receptor expression and reactivity. For the vascular wall to act as a functional unit …

Although radiotherapy is commonly used to treat cancer, its beneficial outcome is frequently
hampered by the radiation resistance of tumor cells and adverse reactions in normal tissues …

Connexin (Cxs) hemichannels participate in several physiological and pathological
processes, but the molecular mechanisms that control their gating remain elusive. We aimed …