Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis

C Granziera, J Wuerfel, F Barkhof, M Calabrese… - Brain, 2021 - academic.oup.com
Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

[HTML][HTML] Advanced spinal cord MRI in multiple sclerosis: Current techniques and future directions

AJE Combes, MA Clarke, KP O'Grady, KG Schilling… - NeuroImage: Clinical, 2022 - Elsevier
Spinal cord magnetic resonance imaging (MRI) has a central role in multiple sclerosis (MS)
clinical practice for diagnosis and disease monitoring. Advanced MRI sequences capable of …

Empirical transmit field bias correction of T1w/T2w myelin maps

MF Glasser, TS Coalson, MP Harms, J Xu, GL Baum… - NeuroImage, 2022 - Elsevier
T1-weighted divided by T2-weighted (T1w/T2w) myelin maps were initially developed for
neuroanatomical analyses such as identifying cortical areas, but they are increasingly used …

Myelin water imaging depends on white matter fiber orientation in the human brain

C Birkl, J Doucette, M Fan… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose The multi‐exponential T2 decay of the MRI signal from cerebral white matter can be
separated into short T2 components related to myelin water and long T2 components related …

[HTML][HTML] Myelin water imaging data analysis in less than one minute

H Liu, QS Xiang, R Tam, AV Dvorak, AL MacKay… - NeuroImage, 2020 - Elsevier
Purpose Based on a deep learning neural network (NN) algorithm, a super fast and easy to
implement data analysis method was proposed for myelin water imaging (MWI) to calculate …

Eccentric rehabilitation induces white matter plasticity and sensorimotor recovery in chronic spinal cord injury

TD Faw, B Lakhani, P Schmalbrock, MV Knopp… - Experimental …, 2021 - Elsevier
Experience-dependent white matter plasticity offers new potential for rehabilitation-induced
recovery after neurotrauma. This first-in-human translational experiment combined myelin …

Brain myelin water fraction and diffusion tensor imaging atlases for 9‐10 year‐old children

SR Morris, RD Holmes, AV Dvorak, H Liu… - Journal of …, 2020 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Myelin water imaging (MWI) and diffusion
tensor imaging (DTI) provide information about myelin and axon‐related brain …

Associations between myelin water imaging and measures of fall risk and functional mobility in multiple sclerosis

EM Edwards, JA Stanley, AM Daugherty… - Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Myelin water fraction (MWF) deficits as measured by
myelin water imaging (MWI) have been related to worse motor function in persons with …

A data‐driven T2 relaxation analysis approach for myelin water imaging: Spectrum analysis for multiple exponentials via experimental condition oriented simulation …

H Liu, TS Joseph, QS Xiang, R Tam… - Magnetic …, 2022 - Wiley Online Library
Purpose The decomposition of multi‐exponential decay data into a T2 spectrum poses
substantial challenges for conventional fitting algorithms, including non‐negative least …

Mapping the rest of the human connectome: atlasing the spinal cord and peripheral nervous system

A Irimia, JD Van Horn - Neuroimage, 2021 - Elsevier
The emergence of diffusion, structural, and functional neuroimaging methods has enabled
major multi-site efforts to map the human connectome, which has heretofore been defined …