Internal m7G methylation: a novel epitranscriptomic contributor in brain development and diseases

X Xia, Y Wang, JC Zheng - Molecular Therapy-Nucleic Acids, 2023 - cell.com
In recent years, N7-methylguanosine (m7G) methylation, originally considered as
messenger RNA (mRNA) 5′ caps modifications, has been identified at defined internal …

RNA epigenetic modifications in ovarian cancer: The changes, chances, and challenges

L Ye, X Yao, B Xu, W Chen, H Lou… - Wiley …, 2023 - Wiley Online Library
Ovarian cancer (OC) is the most common female cancer worldwide. Patients with OC have
high mortality because of its complex and poorly understood pathogenesis. RNA epigenetic …

N7-methylguanosin regulators-mediated methylation modification patterns and characterization of the immune microenvironment in lower-grade glioma

A Maimaiti, Z Feng, Y Liu, M Turhon, Z Xie… - European Journal of …, 2023 - Springer
Abstract N7-methylguanosine (m7G) modification signature has recently emerged as a
crucial regulator of tumor progression and treatment in cancer. However, there is limited …

4acCPred: Weakly supervised prediction of N4-acetyldeoxycytosine DNA modification from sequences

J Zhou, X Wang, Z Wei, J Meng, D Huang - Molecular Therapy-Nucleic …, 2022 - cell.com
DNA methylation is one of the earliest epigenetic regulation mechanisms studied
extensively, and it is critical for normal development, diseases, and gene expression. As a …

Predicting Disease-Associated N7–Methylguanosine (m7G) Sites via Random Walk on Heterogeneous Network

Y Huang, Z Wu, W Lan, C Zhong - IEEE/ACM Transactions on …, 2023 - ieeexplore.ieee.org
Recent studies revealed that the modification of N7-methylguanosine (m 7 G) has
associations with many human diseases. Effectively identifying disease-associated m 7 G …

[HTML][HTML] Recent advances in functional annotation and prediction of the epitranscriptome

SY Zhang, SW Zhang, T Zhang, XN Fan… - Computational and …, 2021 - Elsevier
RNA modifications, in particular N 6-methyladenosine (m 6 A), participate in every stages of
RNA metabolism and play diverse roles in essential biological processes and disease …

RMDGCN: Prediction of RNA methylation and disease associations based on graph convolutional network with attention mechanism

L Liu, Y Zhou, X Lei - PLOS Computational Biology, 2023 - journals.plos.org
RNA modification is a post transcriptional modification that occurs in all organisms and plays
a crucial role in the stages of RNA life, closely related to many life processes. As one of the …

Neuroblastoma susceptibility and association of N7-methylguanosine modification gene polymorphisms: multi-center case-control study

H Lin, F Liao, J Liu, Z Yang, J Zhang, J Cheng… - Pediatric …, 2024 - nature.com
Background Neuroblastoma (NB) is a common extracranial solid malignancy in children.
The N7-methylguanosine (m7G) modification gene METTL1/WDR4 polymorphisms may …

m7G-DPP: Identifying N7-methylguanosine sites based on dinucleotide physicochemical properties of RNA

H Zou, Z Yin - Biophysical Chemistry, 2021 - Elsevier
Abstract N7-methylguanosine (m7G) modification is one of the most common post-
transcriptional RNA modifications, which play vital role in the regulation of gene expression …

A novel serum m7G-harboring microRNA signature for cancer detection

Y Chen, Y Xie, L Bi, H Ci, W Li, D Liu - Frontiers in Genetics, 2024 - frontiersin.org
Background: Emerging evidence points to the exceptional importance and value of m7G
alteration in the diagnosis and prognosis of cancers. Nonetheless, a biomarker for precise …