The link between perturbations in translational control and cancer etiology is becoming a
primary focus in cancer research. It has now been established that genetic alterations in …

Cell proliferation and cell growth are two tightly linked processes, as the proliferation
program cannot be executed without proper accumulation of cell mass, otherwise …

BACKGROUND & AIMS: Aspirin reduces the incidence of and mortality from colorectal
cancer (CRC) by unknown mechanisms. Cancer cells have defects in signaling via the …

Ribosomes are essential components of the protein synthesis machinery. The process of
ribosome biogenesis is well organized and tightly regulated. Recent studies have shown …

MALDI mass spectrometry imaging is able to simultaneously determine the spatial
distribution of hundreds of molecules directly from tissue sections, without labeling and …

A deficiency in pejvakin, a protein of unknown function, causes a strikingly heterogeneous
form of human deafness. Pejvakin-deficient (Pjvk−/−) mice also exhibit variable auditory …

Background RNA from exosomes and other microvesicles contain transcripts of tumour
origin. In this study we sought to identify biomarkers of glioblastoma multiforme in …

The clinical development of anticancer metallodrugs is often hindered by the elusive nature
of their molecular targets. To identify the molecular targets of an antimetastatic ruthenium …

Ribosomal proteins (RPs), the essential components of the ribosome, are a family of RNA-
binding proteins, which play prime roles in ribosome biogenesis and protein translation …

Many studies have focused on understanding the regulation and functions of aberrant
protein synthesis in colorectal cancer (CRC), leaving the ribosome, its main effector …