Causal machine learning for predicting treatment outcomes

S Feuerriegel, D Frauen, V Melnychuk, J Schweisthal… - Nature Medicine, 2024 - nature.com
Causal machine learning (ML) offers flexible, data-driven methods for predicting treatment
outcomes including efficacy and toxicity, thereby supporting the assessment and safety of …

Using machine learning to individualize treatment effect estimation: Challenges and opportunities

A Curth, RW Peck, E McKinney… - Clinical …, 2024 - Wiley Online Library
The use of data from randomized clinical trials to justify treatment decisions for real‐world
patients is the current state of the art. It relies on the assumption that average treatment …

Sharp bounds for generalized causal sensitivity analysis

D Frauen, V Melnychuk… - Advances in Neural …, 2024 - proceedings.neurips.cc
Causal inference from observational data is crucial for many disciplines such as medicine
and economics. However, sharp bounds for causal effects under relaxations of the …

Hidden yet quantifiable: A lower bound for confounding strength using randomized trials

P De Bartolomeis, JA Martinez… - International …, 2024 - proceedings.mlr.press
In the era of fast-paced precision medicine, observational studies play a major role in
properly evaluating new treatments in clinical practice. Yet, unobserved confounding can …

Bayesian neural controlled differential equations for treatment effect estimation

K Hess, V Melnychuk, D Frauen… - arXiv preprint arXiv …, 2023 - arxiv.org
Treatment effect estimation in continuous time is crucial for personalized medicine.
However, existing methods for this task are limited to point estimates of the potential …

A neural framework for generalized causal sensitivity analysis

D Frauen, F Imrie, A Curth, V Melnychuk… - arXiv preprint arXiv …, 2023 - arxiv.org
Unobserved confounding is common in many applications, making causal inference from
observational data challenging. As a remedy, causal sensitivity analysis is an important tool …

Partial counterfactual identification of continuous outcomes with a curvature sensitivity model

V Melnychuk, D Frauen… - Advances in Neural …, 2023 - proceedings.neurips.cc
Counterfactual inference aims to answer retrospective" what if" questions and thus belongs
to the most fine-grained type of inference in Pearl's causality ladder. Existing methods for …

Bounds on Representation-Induced Confounding Bias for Treatment Effect Estimation

V Melnychuk, D Frauen, S Feuerriegel - arXiv preprint arXiv:2311.11321, 2023 - arxiv.org
State-of-the-art methods for conditional average treatment effect (CATE) estimation make
widespread use of representation learning. Here, the idea is to reduce the variance of the …

Partial identification of dose responses with hidden confounders

MG Marmarelis, E Haddad, A Jesson… - Uncertainty in …, 2023 - proceedings.mlr.press
Inferring causal effects of continuous-valued treatments from observational data is a crucial
task promising to better inform policy-and decision-makers. A critical assumption needed to …

Policy Learning for Localized Interventions from Observational Data

MG Marmarelis, F Morstatter… - International …, 2024 - proceedings.mlr.press
A largely unaddressed problem in causal inference is that of learning reliable policies in
continuous, high-dimensional treatment variables from observational data. Especially in the …