The present invention is directed to protocells for specific targeting of hepatocellular and
other cancer cells which comprise a nanoporous silica core with a supported lipid bilayer; at …

5,472,881 A 12/1995 Beebe et al. 5,677.467 A 10/1997 Hoye et al. 6,274,337 B1 8, 2001
Parce et al. 6,361,944 B1 3, 2002 Mirkin et al. 6,506,564 B1 1/2003 Mirkin et al. 7,691,414 …

Aspects of the invention relate to spherical nucleic acid based constructs and related
methods and compositions thereof. The compositions of the invention are useful for …

Ashley, Carlee E. et al. The targeted delivery of multicomponent cargos to cancer cells by
nanoporous particle-supported lipid bilay ers. Nature Materials, 2011; 10: 389-397 …

Certain embodiments described herein include structures having a core-shell type
arrangement; for instance, a nano structure core may be surrounded by a shell including a …

In one embodiment, the invention provides a new design of nanocarrier compositions that
release their therapeutic load specifically at intraperitoneal cancers site. These nanocar riers …

The health risk associated with high cholesterol levels in the human body has motivated
intensive efforts to lower them by using specialized drugs. However, little research has been …

Liposomal spherical nucleic acids that function as multivalent immune modulators are
provided according to the invention. The liposomal spherical nucleic acids of the invention …

US9216155B2 - Synthetic nanostructures including nucleic acids and/or other entities - Google
Patents US9216155B2 - Synthetic nanostructures including nucleic acids and/or other entities …

Aspects of the invention relate to methods for measuring the binding constant of a lipophilic
or amphiphilic molecule acceptor for a lipophilic or amphiphilic molecule. Methods involve …