Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

S Alseekh, A Aharoni, Y Brotman, K Contrepois… - Nature …, 2021 - nature.com
Mass spectrometry-based metabolomics approaches can enable detection and
quantification of many thousands of metabolite features simultaneously. However …

[HTML][HTML] The style and substance of plant flavonoid decoration; towards defining both structure and function

S Alseekh, LP de Souza, M Benina, AR Fernie - Phytochemistry, 2020 - Elsevier
Over 8000 different flavonoids have been described and a considerable number of new
flavonoid structures are being elucidated every year. The advent of metabolomics alongside …

Plant Metabolic Network 15: A resource of genome‐wide metabolism databases for 126 plants and algae

C Hawkins, D Ginzburg, K Zhao… - Journal of integrative …, 2021 - Wiley Online Library
To understand and engineer plant metabolism, we need a comprehensive and accurate
annotation of all metabolic information across plant species. As a step towards this goal, we …

Computational approaches to natural product discovery

MH Medema, MA Fischbach - Nature chemical biology, 2015 - nature.com
Starting with the earliest Streptomyces genome sequences, the promise of natural product
genome mining has been captivating: genomics and bioinformatics would transform …

Carotenoids Database: structures, chemical fingerprints and distribution among organisms

J Yabuzaki - Database, 2017 - academic.oup.com
To promote understanding of how organisms are related via carotenoids, either
evolutionarily or symbiotically, or in food chains through natural histories, we built the …

[HTML][HTML] The secondary metabolite bioinformatics portal: computational tools to facilitate synthetic biology of secondary metabolite production

T Weber, HU Kim - Synthetic and Systems Biotechnology, 2016 - Elsevier
Natural products are among the most important sources of lead molecules for drug
discovery. With the development of affordable whole-genome sequencing technologies and …

Data resources for the computer-guided discovery of bioactive natural products

Y Chen, C de Bruyn Kops… - Journal of chemical …, 2017 - ACS Publications
Natural products from plants, animals, marine life, fungi, bacteria, and other organisms are
an important resource for modern drug discovery. Their biological relevance and structural …

Current challenges in plant eco-metabolomics

K Peters, A Worrich, A Weinhold, O Alka… - International Journal of …, 2018 - mdpi.com
The relatively new research discipline of Eco-Metabolomics is the application of
metabolomics techniques to ecology with the aim to characterise biochemical interactions of …

[HTML][HTML] Natural products chemistry: The emerging trends and prospective goals

RA Khan - Saudi pharmaceutical journal, 2018 - Elsevier
The role and contributions of natural products chemistry in advancements of the physical
and biological sciences, its interdisciplinary domains, and emerging of new avenues by …

Structural characterization of flavonoid glycoconjugates and their derivatives with mass spectrometric techniques

P Kachlicki, A Piasecka, M Stobiecki, Ł Marczak - Molecules, 2016 - mdpi.com
Mass spectrometry is currently one of the most versatile and sensitive instrumental methods
applied to structural characterization of plant secondary metabolite mixtures isolated from …