The dietary consumption of grape and its products is associated with a lower incidence of
degenerative diseases such as cardiovascular disease and certain types of cancers. Most …

Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

Background: SGLT2 (sodium/glucose cotransporter 2) inhibitors exert robust
cardioprotective effects against heart failure in patients with diabetes, and there is intense …

The numerous uses of the grapevine fruit, especially for wine and beverages, have made it
one of the most important plants worldwide. The phytochemistry of grapevine is rich in a …

The aim of this review is to discuss the accumulating evidence that suggests that grape
extracts and purified grape polyphenols possess a diverse array of biological actions and …

Cardiac arrhythmia is one of the most prevalent cardiovascular diseases worldwide, which
can occur alone or be triggered by other diseases, and it can be fatal in severe cases …

Diabetic peripheral neuropathy (DPN) is a common complication affecting more than one
third of diabetes mellitus (DM) patients. Although all cellular components participating in …

Because ion channels are involved in many cellular processes, drugs acting on ion
channels have long been used for the treatment of many diseases, especially those affecting …

Voltage-gated sodium channels (Nav) are modulated by many bilayer mechanical
amphiphiles, but whether, like other voltage-gated channels (Kv, HCN, Cav), they respond to …

Coffee and tea are extensively consumed beverages worldwide which have received
considerable attention regarding health. Intake of these beverages is consistently linked to …