Inflammation‐related mechanisms in chronic kidney disease prediction, progression, and outcome

S Mihai, E Codrici, ID Popescu… - Journal of …, 2018 - Wiley Online Library
Persistent, low‐grade inflammation is now considered a hallmark feature of chronic kidney
disease (CKD), being involved in the development of all‐cause mortality of these patients …

[HTML][HTML] Biological potential and mechanisms of Tea's bioactive compounds: An Updated review

Q Luo, L Luo, J Zhao, Y Wang, H Luo - Journal of Advanced Research, 2024 - Elsevier
Abstract Background Tea (Camellia sinensis) has a rich history and is widely consumed
across many countries, and is categorized into green tea, white tea, oolong tea, yellow tea …

[HTML][HTML] Apoptotic induction and anti-metastatic activity of eugenol encapsulated chitosan nanopolymer on rat glioma C6 cells via alleviating the MMP signaling …

Z Li, VP Veeraraghavan, SK Mohan, SR Bolla… - … of Photochemistry and …, 2020 - Elsevier
Glioma is the prime cause of cancer allied mortality in adolescent people and it accounts
about 80% of all malignant tumours. Eugenol is a major bioactive constituent present in the …

Targeting NF-κB-inducing kinase (NIK) in immunity, inflammation, and cancer

KM Pflug, R Sitcheran - International journal of molecular sciences, 2020 - mdpi.com
NF-κB-inducing kinase (NIK), the essential upstream kinase, which regulates activation of
the noncanonical NF-κB pathway, has important roles in regulating immunity and …

NSAIDs and cancer resolution: new paradigms beyond cyclooxygenase

OR Kolawole, K Kashfi - International journal of molecular sciences, 2022 - mdpi.com
Acute inflammation or resolved inflammation is an adaptive host defense mechanism and is
self-limiting, which returns the body to a state of homeostasis. However, unresolved …

Genetic alterations and their clinical implications in DLBCL

Y Miao, LJ Medeiros, Y Li, J Li, KH Young - Nature reviews Clinical …, 2019 - nature.com
Diffuse large B cell lymphoma (DLBCL) is a highly heterogeneous lymphoid neoplasm with
variations in gene expression profiles and genetic alterations, which lead to substantial …

The transcription factor NF-κB in stem cells and development

C Kaltschmidt, JFW Greiner, B Kaltschmidt - Cells, 2021 - mdpi.com
NF-κB (nuclear factor kappa B) belongs to a family of transcription factors known to regulate
a broad range of processes such as immune cell function, proliferation and cancer …

Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways

AR Afshari, M Sanati, H Mollazadeh… - Seminars in cancer …, 2022 - Elsevier
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

[HTML][HTML] GSK3β as a novel promising target to overcome chemoresistance in pancreatic cancer

C Pecoraro, B Faggion, B Balboni, D Carbone… - Drug Resistance …, 2021 - Elsevier
Pancreatic cancer is an aggressive malignancy with increasing incidence and poor
prognosis due to its late diagnosis and intrinsic chemoresistance. Most pancreatic cancer …

Plants as a source of anticancer agents: From bench to bedside

WH Talib, S Daoud, AI Mahmod, RA Hamed, D Awajan… - Molecules, 2022 - mdpi.com
Cancer is the second leading cause of death after cardiovascular diseases. Conventional
anticancer therapies are associated with lack of selectivity and serious side effects. Cancer …