Inflammation and immune dysfunction in Parkinson disease

MG Tansey, RL Wallings, MC Houser… - Nature Reviews …, 2022 - nature.com
Parkinson disease (PD) is a progressive neurodegenerative disease that affects peripheral
organs as well as the central nervous system and involves a fundamental role of …

The neuropsychiatry of Parkinson's disease: advances and challenges

D Weintraub, D Aarsland, KR Chaudhuri… - The Lancet …, 2022 - thelancet.com
In people with Parkinson's disease, neuropsychiatric signs and symptoms are common
throughout the disease course. These symptoms can be disabling and as clinically relevant …

Cannabinoids: therapeutic use in clinical practice

C Pagano, G Navarra, L Coppola, G Avilia… - International journal of …, 2022 - mdpi.com
Medical case reports suggest that cannabinoids extracted from Cannabis sativa have
therapeutic effects; however, the therapeutic employment is limited due to the psychotropic …

Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Cannabinoid formulations and delivery systems: Current and future options to treat pain

B Stella, F Baratta, C Della Pepa, S Arpicco, D Gastaldi… - Drugs, 2021 - Springer
The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …

MicroRNA dysregulation in Parkinson's disease: a narrative review

YH Nies, NH Mohamad Najib, WL Lim… - Frontiers in …, 2021 - frontiersin.org
Parkinson's disease (PD) is a severely debilitating neurodegenerative disease, affecting the
motor system, leading to resting tremor, cogwheel rigidity, bradykinesia, walking and gait …

Impacts of medical and non-medical cannabis on the health of older adults: findings from a scoping review of the literature

D Wolfe, K Corace, C Butler, D Rice, B Skidmore… - PLoS …, 2023 - journals.plos.org
Background Cannabis legalization has enabled increased consumption in older adults. Age-
related mental, physical, and physiological changes may lead to differences in effects of …

Pharmacological treatment of tremor in Parkinson's disease revisited

W Pirker, R Katzenschlager, M Hallett… - Journal of Parkinson's …, 2023 - content.iospress.com
The pathophysiology of Parkinson's disease (PD) tremor remains incompletely understood
and there is a lack of clinical trials specifically addressing its pharmacological treatment …

Medical cannabis and cannabinoids for impaired sleep: a systematic review and meta-analysis of randomized clinical trials

M AminiLari, L Wang, S Neumark, T Adli, RJ Couban… - Sleep, 2022 - academic.oup.com
Abstract Study Objectives We conducted a systematic review to explore the effectiveness of
medical cannabis for impaired sleep. Methods We searched MEDLINE, EMBASE …

Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications

A Bilbao, R Spanagel - BMC medicine, 2022 - Springer
Background Medical cannabinoids differ in their pharmacology and may have different
treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and …