Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor
metabolism is again in the spotlight of cancer research. Many studies have been carried out …

Metabolic switches are a crucial hallmark of cellular development and regeneration. In
response to changes in their environment or physiological state, cells undergo coordinated …

Pollen grains become increasingly independent of the mother plant as they reach maturity
through poorly understood developmental programs. We report that the hormone auxin is …

During embryonic development, cells exit pluripotency to give rise to the three germ layers.
Metabolic pathways influence cell fate decisions by modulating the epigenetic …

Highly potent animal stem cells either self renew or launch complex differentiation programs,
using mechanisms that are only partly understood. Drosophila female germline stem cells …

Choroid plexus (ChP), a vascularized secretory epithelium located in all brain ventricles,
plays critical roles in development, homeostasis and brain repair. Reverse transcription …

Metabolism is crucial for development through supporting cell growth, energy production,
establishing cell identity, developmental signaling and pattern formation. In many model …

Gut microbiota have been shown to promote oogenesis and fecundity, but the mechanistic
basis of remote influence on oogenesis remained unknown. Here, we report a systemic …

The transition from oocyte to embryo marks the onset of development. This process requires
complex regulation to link developmental signals with profound changes in mRNA …

Cellular metabolic reprogramming is an important mechanism by which cells rewire their
metabolism to promote proliferation and cell growth. This process has been mostly studied …