Knowledge on the genetic basis of Parkinson's disease has grown tremendously since the
discovery of the first monogenic form, caused by a mutation in α-synuclein, and with the …

Pathogenic variants in the LRRK2 gene are one of the most commonly identifiable
monogenic causes of Parkinson's disease (PD, PARK-LRRK2). This systematic MDSGene …

This scientific commentary refers to 'Relevance of genetic testing in the gene-targeted trial
era: the Rostock Parkinson's Disease Study'by Westenberger et al.(https://doi …

Background Progressive supranuclear palsy (PSP) is largely a sporadic disease with few
reported familial cases. Genome‐wide association studies (GWAS) in sporadic PSP in …

Pathogenic variants in the Leucine-rich repeat kinase 2 (LRRK2) gene are a primary
monogenic cause of Parkinson's disease (PD). However, the likelihood of developing PD …

Introduction Parkinson's disease (PD) is a complex disorder with vast clinical heterogeneity.
Recent genetic, imaging and clinical evidence suggest that there are multiple subtypes of …

Abstract Background The p. Ser71Arg RAB32 variant was recently associated with
Parkinson's disease (PD). Objective The aim was to investigate the presence of RAB32 …

Parkinson's disease (PD) is considered to be the second most prominent neurodegenerative
disease and has a global prevalence. Glucocerebrosidase (GBA1) gene mutations …

Background and Objectives In the era of precision medicine, genetic test results have
become increasingly relevant in the care of patients with Parkinson disease (PD). While …

Objectives: Our aim was to evaluate the possible long-term cerebral deposition of amyloid-β
in patients with PD treated with subthalamic nucleus deep brain stimulation (STN-DBS) and …