The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …

Extracellular vesicles (EVs) are a means of cell-to-cell communication and can facilitate the
exchange of a broad array of molecules between adjacent or distant cells. Platelets are …

Rationale: Coronavirus disease 2019 (COVID-19) is characterized by increased incidence
of microthrombosis with hyperactive platelets sporadically containing viral RNA. It is unclear …

The release of growth factors, cytokines and extracellular matrix modifiers by activated
platelets is an important step in the process of healthy wound healing. Extracellular vesicles …

Classically, platelets have been described as the cellular blood component that mediates
hemostasis and thrombosis. This important platelet function has received significant …

There is much interest in the use of extracellular vesicles (EVs) as a subcellular therapy for
regenerative medicine and drug delivery. Blood-borne platelets represent a source of …

Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are
now known to mediate physiological and pathological functions throughout the body. We …

There is an urgent need to understand the underlying mechanisms contributing to
thrombotic and inflammatory complications during COVID‐19. Data from independent …

In addition to their hemostatic role, platelets play a significant role in immunity. Once
activated, platelets release extracellular vesicles (EVs) formed by the budding of their …

Extracellular vesicles (EVs) are cell-derived lipid bilayer-enclosed particles that play a role
in intercellular communication. Cardiac progenitor cell (CPC)-derived EVs have been shown …