Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the International Immuno …

S Hendry, R Salgado, T Gevaert… - Advances in anatomic …, 2017 - journals.lww.com
Assessment of the immune response to tumors is growing in importance as the prognostic
implications of this response are increasingly recognized, and as immunotherapies are …

Assessing tumor-infiltrating lymphocytes in solid tumors: a practical review for pathologists and proposal for a standardized method from the international …

S Hendry, R Salgado, T Gevaert… - Advances in anatomic …, 2017 - journals.lww.com
Assessment of tumor-infiltrating lymphocytes (TILs) in histopathologic specimens can
provide important prognostic information in diverse solid tumor types, and may also be of …

[HTML][HTML] Systemic inflammation in colorectal cancer: Underlying factors, effects, and prognostic significance

AE Tuomisto, MJ Mäkinen… - World journal of …, 2019 - ncbi.nlm.nih.gov
Systemic inflammation is a marker of poor prognosis preoperatively present in around 20%-
40% of colorectal cancer patients. The hallmarks of systemic inflammation include an …

Towards the introduction of the 'Immunoscore'in the classification of malignant tumours

J Galon, B Mlecnik, G Bindea, HK Angell… - The Journal of …, 2014 - Wiley Online Library
Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine …

Report on computational assessment of tumor infiltrating lymphocytes from the International Immuno-Oncology Biomarker Working Group

M Amgad, ES Stovgaard, E Balslev, J Thagaard… - NPJ breast …, 2020 - nature.com
Assessment of tumor-infiltrating lymphocytes (TILs) is increasingly recognized as an integral
part of the prognostic workflow in triple-negative (TNBC) and HER2-positive breast cancer …

[HTML][HTML] Strategies for clinical implementation of TNM-Immunoscore in resected nonsmall-cell lung cancer

T Donnem, TK Kilvaer, S Andersen, E Richardsen… - Annals of oncology, 2016 - Elsevier
Immunoscore is a prognostic tool defined to quantify in situ immune cell infiltrates and
appears highly promising as a supplement to the tumor–node–metastasis (TNM) …

IL-17/Th17 pathway is activated in acne lesions

HL Kelhälä, R Palatsi, N Fyhrquist, S Lehtimäki… - PloS one, 2014 - journals.plos.org
The mechanisms of inflammation in acne are currently subject of intense investigation. This
study focused on the activation of adaptive and innate immunity in clinically early visible …

Detailed analysis of inflammatory cell infiltration in colorectal cancer

JP Väyrynen, A Tuomisto, K Klintrup, J Mäkelä… - British journal of …, 2013 - nature.com
Background: Higher-grade inflammatory infiltrate is a promising marker for better prognosis
in colorectal cancer (CRC). However, the knowledge on the interrelationships between …

Prognostic and predictive role of tumour-associated macrophages in HER2 positive breast cancer

TJ Honkanen, A Tikkanen, P Karihtala, M Mäkinen… - Scientific reports, 2019 - nature.com
Disease outcomes of HER2+ breast cancers have dramatically improved after targeted
therapies, such as trastuzumab became available. The main mechanism of action of …

Pressure-activatable liquid metal composites flexible sensor with antifouling and drag reduction functional surface

Z Ma, S Lu, Y Wu, X Zhang, Y Wei… - … Applied Materials & …, 2023 - ACS Publications
Flexible sensors produced through three-dimensional (3D) printing have exhibited
promising results in the context of underwater sensing detection (for applications in …