Methylglyoxal is an α-oxoaldehyde inevitably produced from triose-phosphate intermediates
of phosphorylating glycolysis, and also from amino acids and acetone. Recently, the …

Diabetes Mellitus (DM) is one among the supreme metabolic issues observed in history
since 3000 BCE and has gained much interest recently due to the increasing number of …

Diabetic nephropathy (DN) is a major cause of end-stage renal disease, and therapeutic
options for preventing its progression are limited. To identify novel therapeutic strategies, we …

摘要背景: 甲基乙二醛(Methylglyoxal, MG) 是一种活性二羰基, 被认为是晚期糖化终产物的前体
或具有直接的毒性, 进而促进糖尿病的发展. 本研究的目的是测定初诊2 型糖尿病患者血浆MG …

The determination of methylglyoxal (MG) concentrations in vivo is gaining increasing
importance as high levels of MG are linked to various health impairments including …

Methylglyoxal (MGO), a dicarbonyl metabolite produced by all living cells, has been
associated with a number of human diseases. However, studies of the role (s) MGO plays …

Background: The reactive α-oxoaldehydes glyoxal (GO), methylglyoxal (MGO) and 3-
deoxyglucosone (3-DG) have been linked to diabetic complications and other age-related …

Previous studies have demonstrated that reactive dicarbonyl compounds [eg, methylglyoxal
(MGO) and glyoxal (GO)] irreversibly and progressively modify proteins over time and yield …

Diabetes increases the percentage of circulating erythrocytes exposing phosphatidylserine
(PS) at the cell surface. PS-exposing erythrocytes are recognized, bound, engulfed and …

Methylglyoxal (MG) is a highly reactive α‐oxoaldehyde formed endogenously in numerous
enzymatic and nonenzymatic reactions. It modifies arginine and lysine residues in proteins …