Exposure to certain acute and chronic stressors results in an immediate behavioral and
physiological response to the situation followed by a period of days when cross-sensitization …

Severe socioeconomic deprivation (SED) and adverse childhood experiences (ACE) are
significantly associated with the development in adulthood of (i) enhanced inflammatory …

Psychosocial stress triggers a set of behavioral, neural, hormonal, and molecular responses
that can be a driving force for survival when adaptive and time-limited, but may also …

There is an ongoing debate about the value of animal research in psychiatry with valid lines
of reasoning stating the limits of individual animal models compared to human psychiatric …

Fear-, anxiety-and stress-related disorders are among the most frequent mental disorders.
Given substantial rates of insufficient treatment response and often a chronic course, a better …

Psychological stress increases intestinal permeability, potentially leading to low-grade
inflammation and symptoms in functional gastrointestinal disorders. We assessed the effect …

Previous experience of chronic pain causes enhanced responses to upcoming noxious
events in both humans and animals, but the underlying mechanisms remain unclear. In the …

The aim of this study was to determine whether mental stress moderates perceptions of
muscular pain, exertion, pleasure and arousal during a bout of strenuous resistance …

Sustained stimulation of G-protein-coupled receptors (GPCRs) typically causes receptor
desensitisation, which is mediated by phosphorylation, often within the C-terminal tail of the …

There is a wealth of data indicating that de novo protein S-nitrosylation in general and
protein transnitrosylation in particular mediates the bulk of nitric oxide signalling. These …