Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Fibrosis is the extensive deposition of fibrous connective tissue, and it is characterized by
the accumulation of collagen and other extracellular matrix (ECM) components. Fibrosis is …

A scar is an expected result of wound healing. However, in some individuals, and
particularly in burn victims, the wound healing processes may lead to a fibrotic hypertrophic …

Epithelial-mesenchymal transition (EMT), characterized by loss of epithelial adhesion and
gain of mesenchymal features, is an important mechanism to empower epithelial cells into …

Objective To describe the clinical characteristics of postburn scars and determine the
independent risk factors specific to these patients. While burns may generate widespread …

The healing of a skin wound is a complex process involving many cell lineages. In adult
tissues, repair is always accompanied by a robust inflammatory response, which is …

Purpose: Human limbal palisade of Vogt is an ideal model for studying and practicing
regenerative medicine due to their accessibility. Nonresolving inflammation is a common …

Fibrosis is an important health problem, and its pathogenetic principles are still largely
unknown. It can develop either spontaneously, or, more frequently, as a consequence of …

Background Keloid disease (KD) is a common fibroproliferative disorder of unknown
aetiology. T cells and macrophages are increased in KD and are thought to contribute to its …