KRAS mutations are the drivers of various cancers, including non–small cell lung cancer,
colon cancer, and pancreatic cancer. Over the last 30 years, immense efforts have been …

Colorectal cancer (CRC) represents one of the most commonly diagnosed cancers
worldwide. It is the second leading cause of cancer death in Western Countries. In the last …

Results: The study analyzed 58 men and 33 women, mean age 66.6 years, with the
youngest patient at age of 35 and the oldest at age of 89 years. The largest number of …

The increasing interest of the oncology community in tumour classification and prediction of
outcome to targeted therapies has put emphasis on an improved identification of tumour …

Background: Since the first introduction of tumour markers, their usefulness for diagnosis
has been a challenging question. The aim of the present prospective study was to …

Objective: The purpose of this study was to explore the relationship between the levels of
three tumor markers (TMs), carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19 …

Background Clinicopathologic characteristics and prognostic and predictive factors offer
valuable guidance when selecting optimal first-line treatment in patients with metastatic …

Objective• To investigate the clinical diagnostic and prognostic value of preoperative serum
tumor markers in patients with colorectal cancer (CRC). Methods• From September 2013 to …

Background Carbohydrate antigen 19–9 (CA 19–9) is one of the most frequently used tumor
markers for gastrointestinal cancer, particularly for diagnostic purposes. However, its value …

Mutant KRAS promotes the proliferation, metastasis, and aggressiveness of various cancers
including pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC) …