Many epithelial tumors grow in the vicinity of or metastasize to adipose tissue. As tumors
develop, crosstalk between adipose tissue and cancer cells leads to changes in adipocyte …

Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

Rapid neutrophil recruitment to sites of inflammation is crucial for innate immune responses.
Here, we reveal that the G-protein-coupled receptor GPR35 is upregulated in activated …

Fibroblastic stromal cells are as diverse, in origin and function, as the niches they fashion in
the mammalian body. This cellular variety impacts the spectrum of responses elicited by the …

Tumor-associated tertiary lymphoid structures (TA-TLS) are associated with enhanced
patient survival and responsiveness to cancer therapies, but the mechanisms underlying …

White adipose tissue (WAT) is a cellularly heterogeneous endocrine organ that not only
serves as an energy reservoir, but also actively participates in metabolic homeostasis …

The peritoneal cavity is a fluid filled space that holds most of the abdominal organs,
including the omentum, a visceral adipose tissue that contains milky spots or clusters of …

Ischemia reperfusion injury represents a common pathological condition that is triggered by
the release of endogenous ligands. While neutrophils are known to play a critical role in its …

Peritoneal fibrosis is characterized by abnormal production of extracellular matrix proteins
leading to progressive thickening of the submesothelial compact zone of the peritoneal …

Two resident macrophage subsets reside in peritoneal fluid. Macrophages also reside within
mesothelial membranes lining the peritoneal cavity, but they remain poorly characterized …