Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectives

S Datta, D Aggarwal, N Sehrawat, M Yadav, V Sharma… - Phytomedicine, 2023 - Elsevier
Background: The liver is a well-known player in the metabolism and removal of drugs. Drug
metabolizing enzymes in the liver detoxify drugs and xenobiotics, ultimately leading to the …

A clathrin-related protein FaRRP1/SCD2 integrates ABA trafficking and signaling to regulate strawberry fruit ripening

J Li, Y Shen - Journal of Biological Chemistry, 2023 - ASBMB
Abscisic acid (ABA) is a critical regulator for nonclimacteric fruit ripening such as in the
model plant of strawberry (Fragaria× ananassa). Although FaRRP1 is proposed to …

Identification of MDM2 as a prognostic and immunotherapeutic biomarker in a comprehensive pan-cancer analysis: A promising target for breast cancer, bladder …

J Zheng, F Miao, Z Wang, Y Ma, Z Lin, Y Chen, X Kong… - Life Sciences, 2023 - Elsevier
Background The murine double minute 2 (MDM2) gene is a crucial factor in the
development and progression of various cancer types. Multiple rigorous scientific studies …

Profiling of antioxidant properties and identification of potential analgesic inhibitory activities of Allophylus villosus and Mycetia sinensis employing in vivo, in vitro, and …

MNK Azam, P Biswas, A Khandker, MMI Tareq… - Journal of …, 2025 - Elsevier
Ethnopharmacological relevance The traditional use of plants for medicinal purposes, called
phytomedicine, has been known to provide relief from pain. In Bangladesh, the Chakma …

Antibacterial activity and antibacterial mechanism of flavaspidic acid BB against Staphylococcus haemelyticus

J Liu, R Liu, R Deng, S Zheng, Z Shen - BMC microbiology, 2023 - Springer
Background Staphylococcus haemolyticus (S. haemolyticus) is the main etiological factor in
skin and soft tissue infections (SSTI). S. haemolyticus infections are an important concern …

[HTML][HTML] Phyllanthus emblica (Amla) methanolic extract regulates multiple checkpoints in 15-lipoxygenase mediated inflammopathies: Computational simulation and in …

MA Sharif, AM Khan, R Salekeen, MH Rahman… - Saudi Pharmaceutical …, 2023 - Elsevier
Amla (Phyllanthus emblica) has long been used in traditional folk medicine to prevent and
cure a variety of inflammatory diseases. In this study, the antioxidant activity (DPPH …

Elucidating gastric cancer mechanisms and therapeutic potential of Adociaquinone A targeting EGFR: A genomic analysis and Computer Aided Drug Design (CADD) …

MA Alkhateeb, NH Aljarba, Q Yousafi… - Journal of Cellular …, 2024 - Wiley Online Library
Gastric cancer predominantly adenocarcinoma, accounts for over 85% of gastric cancer
diagnoses. Current therapeutic options are limited, necessitating the discovery of novel drug …

Bioactive phytocompounds profiling and the evaluation of analgesic, anti-inflammatory, and antihyperglycemic potential of Argyreia capitiformis (Poir.) Ooststr.: A …

HS Devnath, P Biswas, DS Oisay, MM Medha… - Journal of …, 2025 - Elsevier
Abstract Ethnopharmacological relevance Argyreia capitiformis (Poir.) Ooststr.(
Convolvulaceae) is traditionally used by the Chakma community in the hilly region of …

[HTML][HTML] Identification of antidiabetic inhibitors from Allophylus villosus and Mycetia sinensis by targeting α-glucosidase and PPAR-γ: In-vitro, in-vivo, and …

MNK Azam, P Biswas, MMI Tareq, MR Hossain… - Saudi Pharmaceutical …, 2024 - Elsevier
Diabetes mellitus (DM) is a metabolic disorder arising from insulin deficiency and
defectiveness of the insulin receptor functioning on transcription factor where the body loses …

[HTML][HTML] Anti-adherent effects of Rhizophora apiculata bark and leaf extracts and computational prediction of the effects of its compound on β-tubulin interaction in …

S Chimplee, I Sama-ae, S Sangkanu… - Veterinary …, 2024 - pmc.ncbi.nlm.nih.gov
Background and Aim: Acanthamoeba, an opportunistic protozoan, exists widely in natural
sources and can cause infections in humans and animals. The absence of effective …