Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward

AK Nanayakkara, HW Boucher… - CA: a cancer journal …, 2021 - Wiley Online Library
Infection is the second leading cause of death in patients with cancer. Loss of efficacy in
antibiotics due to antibiotic resistance in bacteria is an urgent threat against the continuing …

Hypervirulent Klebsiella pneumoniae – clinical and molecular perspectives

JE Choby, J Howard‐Anderson… - Journal of internal …, 2020 - Wiley Online Library
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a concerning global
pathogen. hvKp is more virulent than classical K. pneumoniae (cKp) and capable of causing …

Klebsiella pneumoniae infection biology: living to counteract host defences

JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

[HTML][HTML] Colonization, Infection, and the Accessory Genome of Klebsiella pneumoniae

RM Martin, MA Bachman - Frontiers in cellular and infection …, 2018 - frontiersin.org
Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

[HTML][HTML] A global perspective on the convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae

P Lan, Y Jiang, J Zhou, Y Yu - Journal of global antimicrobial resistance, 2021 - Elsevier
Hypervirulence and carbapenem resistance have emerged as two distinct evolutionary
directions for Klebsiella pneumoniae, which pose a great threat in clinical settings. Multiple …

[HTML][HTML] Virulence Factors in Hypervirulent Klebsiella pneumoniae

J Zhu, T Wang, L Chen, H Du - Frontiers in microbiology, 2021 - frontiersin.org
Hypervirulent Klebsiella pneumoniae (hvKP) has spread globally since first described in the
Asian Pacific Rim. It is an invasive variant that differs from the classical K. pneumoniae …

[HTML][HTML] Antimicrobial Resistance of Hypervirulent Klebsiella pneumoniae: Epidemiology, Hypervirulence-Associated Determinants, and Resistance Mechanisms

CR Lee, JH Lee, KS Park, JH Jeon, YB Kim… - Frontiers in cellular …, 2017 - frontiersin.org
Klebsiella pneumoniae is one of the most clinically relevant species in immunocompromised
individuals responsible for community-acquired and nosocomial infections, including …

[HTML][HTML] High Prevalence of Multidrug-Resistant Klebsiella pneumoniae Harboring Several Virulence and β-Lactamase Encoding Genes in a Brazilian Intensive Care …

RL Ferreira, BCM Da Silva, GS Rezende… - Frontiers in …, 2019 - frontiersin.org
Klebsiella pneumoniae is an important opportunistic pathogen that commonly causes
nosocomial infections and contributes to substantial morbidity and mortality. We sought to …

Hypervirulent klebsiella pneumoniae

TA Russo, CM Marr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Hypervirulent K. pneumoniae (hvKp) is an evolving pathotype that is more virulent than
classical K. pneumoniae (cKp). hvKp usually infects individuals from the community, who are …