Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
implicated to an array of bioactivities investigated by a series of preclinical and clinical …
Recent Trends in the Synthesis and Bioactivity of Coumarin, Coumarin–Chalcone, and Coumarin–Triazole Molecular Hybrids
Molecular hybridization represents a new approach in drug discovery in which specific
chromophores are strategically combined to create novel drugs with enhanced therapeutic …
chromophores are strategically combined to create novel drugs with enhanced therapeutic …
Design and synthesis of methoxyphenyl-and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of …
Exaggerated inflammatory responses may cause serious and debilitating diseases such as
acute lung injury and rheumatoid arthritis. Two series of chalcone derivatives were prepared …
acute lung injury and rheumatoid arthritis. Two series of chalcone derivatives were prepared …
[PDF][PDF] BIOLOGICAL ACTIVITY OF CHALCONES AS CARBONYL COMPOUND DERIVATIVES.
G Binate, K Ganbarov - Advances in Biology & Earth Sciences, 2023 - researchgate.net
Microbial infections remain serious diseases and their frequency continues to increase. It is
therefore essential to find effective therapeutic agents with the least side effects. Chalcones …
therefore essential to find effective therapeutic agents with the least side effects. Chalcones …
[HTML][HTML] Elucidating molecular mechanism and chemical space of chalcones through biological networks and machine learning approaches
We developed a bio-cheminformatics method, exploring disease inhibition mechanisms
using machine learning-enhanced quantitative structure-activity relationship (ML-QSAR) …
using machine learning-enhanced quantitative structure-activity relationship (ML-QSAR) …
[HTML][HTML] Simple and solvent free practical procedure for chalcones: An expeditious, mild and greener approach
An extremely simple, expeditious and greener synthetic method for a variety of chalcone
derivatives (3) under mild and solvent free reaction conditions has been developed. The …
derivatives (3) under mild and solvent free reaction conditions has been developed. The …
Synthesis and in-silico molecular modelling, DFT studies, antiradical and antihyperglycemic activity of novel vanadyl complexes based on chalcone derivatives
Diabetes mellitus (DM) will be one of the ten most deadly diseases in the near future,
according to a WHO survey. It is, therefore, of utmost importance to design and synthesize …
according to a WHO survey. It is, therefore, of utmost importance to design and synthesize …
Attenuation of Quorum Sensing Mediated Virulence Factors and Biofilm Formation in Pseudomonas Aeruginosa PAO1 by Substituted Chalcones and Flavonols
Flavonoids epitomize structural scaffolds in many biologically active synthetic and natural
compounds. They showcase a diverse spectrum of biological activities including anticancer …
compounds. They showcase a diverse spectrum of biological activities including anticancer …
Synthesis, Biological Properties, In Silico ADME, Molecular Docking Studies, and FMO Analysis of Chalcone Derivatives as Promising Antioxidant and Antimicrobial …
R Ahsan, S Paul, MS Alam, AFMM Rahman - ACS Omega, 2025 - ACS Publications
A series of chalcone derivatives were synthesized and characterized using UV–vis, FT-IR,
1H NMR, and mass spectrometry, followed by the evaluation of their antimicrobial and …
1H NMR, and mass spectrometry, followed by the evaluation of their antimicrobial and …
[PDF][PDF] In-silico modelling of 1-3-[3-(substituted phenyl) prop-2-enoyl) phenyl thiourea against anti-inflammatory drug targets
S Sengupta, R Bhowmik, S Acharjee… - Biosciences …, 2021 - academia.edu
The main objective of this present study was to analyze the anti-inflammatory activity of the
compound 1-3-[3-(substituted phenyl) prop-2-enoyl) phenyl thiourea against inflammation …
compound 1-3-[3-(substituted phenyl) prop-2-enoyl) phenyl thiourea against inflammation …