Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases
S Mishra, SS Verma, V Rai, N Awasthee… - Cellular and Molecular …, 2019 - Springer
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …
[HTML][HTML] Long non-coding RNAs regulated NF-κB signaling in cancer metastasis: Micromanaging by not so small non-coding RNAs
Cancer metastasis is a major reason for the cancer-associated deaths and a role of long non-
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …
coding RNAs (lncRNAs) in cancer metastasis is increasingly being realized. Among the …
Regulation of long non-coding RNAs by plant secondary metabolites: a novel anticancer therapeutic approach
MR Kalhori, H Khodayari, S Khodayari, M Vesovic… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is caused by the rapid and uncontrolled growth of cells that
eventually lead to tumor formation. Genetic and epigenetic alterations are among the most …
eventually lead to tumor formation. Genetic and epigenetic alterations are among the most …
The tea catechin epigallocatechin gallate inhibits NF-κB-mediated transcriptional activation by covalent modification
SP Lakshmi, AT Reddy, LD Kodidhela… - Archives of Biochemistry …, 2020 - Elsevier
Potential health benefits of consuming tea are thought to include anti-inflammatory actions of
its constituent flavonoids including catechins, which are well-recognized antioxidants. We …
its constituent flavonoids including catechins, which are well-recognized antioxidants. We …
Calebin A potentiates the effect of 5-FU and TNF-β (lymphotoxin α) against human colorectal cancer cells: potential role of NF-κB
C Buhrmann, AB Kunnumakkara, B Popper… - International journal of …, 2020 - mdpi.com
Objective: The majority of chemotherapeutic agents stimulate NF-κB signaling that mediates
cell survival, proliferation and metastasis. The natural turmeric non-curcuminoid derivate …
cell survival, proliferation and metastasis. The natural turmeric non-curcuminoid derivate …
Thiol dependent NF-κB suppression and inhibition of T-cell mediated adaptive immune responses by a naturally occurring steroidal lactone Withaferin A
Withaferin A (WA), a steroidal lactone isolated from ayurvedic medicinal plant Withania
somnifera, was shown to inhibit tumor growth by inducing oxidative stress and suppressing …
somnifera, was shown to inhibit tumor growth by inducing oxidative stress and suppressing …
Anti-cancer activities of Bharangin against breast cancer: Evidence for the role of NF-κB and lncRNAs
N Awasthee, V Rai, SS Verma, KS Francis… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Breast cancer remains one of the leading causes of cancer related deaths in women
worldwide. Bharangin is a diterpenoid quinonemethide that has demonstrated therapeutic …
worldwide. Bharangin is a diterpenoid quinonemethide that has demonstrated therapeutic …
Piperlongumine chemosensitizes tumor cells through interaction with cysteine 179 of IκBα kinase, leading to suppression of NF-κB–regulated gene products
Recently, two different reports appeared in prominent journals suggesting a mechanism by
which piperlongumine, a pyridine alkaloid, mediates anticancer effects. In the current report …
which piperlongumine, a pyridine alkaloid, mediates anticancer effects. In the current report …
Calebin A, a novel component of turmeric, suppresses NF-κB regulated cell survival and inflammatory gene products leading to inhibition of cell growth and …
Background While the anti-inflammatory and anticancer potential of curcumin, which is
derived from turmeric (Curcuma longa), has been studied extensively, very little is known …
derived from turmeric (Curcuma longa), has been studied extensively, very little is known …
Isodeoxyelephantopin, a sesquiterpene lactone induces ROS generation, suppresses NF-κB activation, modulates LncRNA expression and exhibit activities against …
The sesquiterpene lactones, Isodeoxyelephantopin (IDET) and Deoxyelephantopin (DET)
are known to exhibit activities against some cancer types. The activities of these lactones …
are known to exhibit activities against some cancer types. The activities of these lactones …