There are many differences in arterial diseases between men and women, including
prevalence, clinical manifestations, treatments, and prognosis. The new policy of the …

Cardiovascular disease remains the leading cause of morbidity and mortality for women in
United States and worldwide. One in 3 women dies from cardiovascular disease, and 45 …

Marfan syndrome (MFS) is an autosomal dominant, age-related but highly penetrant
condition with substantial intrafamilial and interfamilial variability. MFS is caused by …

Despite its higher prevalence among men, women with thoracic aortic aneurysm and
dissection (TAAD) have lower rates of treatment and surgical intervention and often have …

Background: Marfan syndrome can cause life-threatening aortic complications. We
investigated the relationship between FBN1 genotype and severe aortopathy (aortic root …

Vascular Ehlers-Danlos syndrome (vEDS) is an autosomal-dominant connective tissue
disorder caused by heterozygous mutations in the COL3A1 gene, which encodes the pro-α …

Background Cardiovascular disease is the leading cause of death during pregnancy with
thoracic aortic dissection being one of the main causes. Thoracic aortic disease is commonly …

Aortopathy encompasses a spectrum of conditions predisposing to dilation, aneurysm,
dissection, or rupture of the aorta and other blood vessels. Aortopathy is diagnosed …

Introduction Valve-sparing root replacement (VSRR) of the ascending aorta is a life-saving
procedure for the treatment of aortic aneurysms, but patients remain at risk for post-operative …

There has been increasing recognition of important sex differences in the development,
management, and outcomes of cardiovascular diseases. Identifying and understanding why …