When detergents and phospholipid membranes are dispersed in aqueous solutions, they tend to self-assemble into vesicles of various shapes and sizes by virtue of their hydrophobic …
M Wu, Y Ouyang, Z Wang, R Zhang… - Proceedings of the …, 2017 - National Acad Sciences
Exosomes are nanoscale extracellular vesicles that play an important role in many biological processes, including intercellular communications, antigen presentation, and the …
H Li, Y Ouyang, E Sadovsky, WT Parks, T Chu… - …, 2020 - Am Heart Assoc
Although preeclampsia is a common and serious complication of pregnancy, insight into its pathobiology and diagnosis is lacking. Circulating plasma exosomes, which contain RNA …
W Li, M Deng, PA Loughran, M Yang, M Lin… - Frontiers in …, 2020 - frontiersin.org
High-mobility group box-1 (HMGB1), a ubiquitous nuclear protein, acts as a late mediator of lethality when released extracellularly during sepsis. The major source of circulating HMGB1 …
M Gauster, G Moser, S Wernitznig, N Kupper… - Cellular and Molecular …, 2022 - Springer
Human pregnancy depends on the proper development of the embryo prior to implantation and the implantation of the embryo into the uterine wall. During the pre-implantation phase …
Serving as the interface between fetal and maternal circulation, the placenta plays a critical role in fetal growth and development. Placental exosomes are small membrane-bound …
MVC Barnes, P Pantazi, B Holder - Journal of Extracellular …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) play a crucial role in pregnancy, revealed by the presence of placental‐derived EVs in maternal blood, their in vitro functionality, and their altered cargo in …
Expression of microRNAs (miRNAs) is essential for embryonic development and serves important roles in gametogenesis. miRNAs are secreted into the extracellular environment …
Extracellular vesicles (EVs) have recently attracted a great deal of interest as they may represent a new biosignaling paradigm. According to the mode of biogenesis, size and …