The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

IL-7: A promising adjuvant ensuring effective T cell responses and memory in combination with cancer vaccines?

Y Zhao, K Wei, H Chi, Z Xia, X Li - Frontiers in Immunology, 2022 - frontiersin.org
Cancer vaccines exhibit specificity, effectiveness, and safety as an alternative
immunotherapeutic strategy to struggle against malignant diseases, especially with the rapid …

[HTML][HTML] Immunogenic ferroptosis and where to find it?

R Demuynck, I Efimova, F Naessens… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Ferroptosis is a recently discovered form of regulated cell death that is morphologically,
genetically, and biochemically distinct from apoptosis and necroptosis, and its potential use …

The screening, identification, design and clinical application of tumor-specific neoantigens for TCR-T cells

J Li, Z Xiao, D Wang, L Jia, S Nie, X Zeng, W Hu - Molecular Cancer, 2023 - Springer
Recent advances in neoantigen research have accelerated the development of tumor
immunotherapies, including adoptive cell therapies (ACTs), cancer vaccines and antibody …

mRNA-based cancer vaccines: a therapeutic strategy for the treatment of melanoma patients

M Bidram, Y Zhao, NG Shebardina, AV Baldin… - Vaccines, 2021 - mdpi.com
Malignant melanoma is one of the most aggressive forms of cancer and the leading cause of
death from skin tumors. Given the increased incidence of melanoma diagnoses in recent …

Recent advances in cancer vaccines: challenges, achievements, and futuristic prospects

M Gupta, A Wahi, P Sharma, R Nagpal, N Raina… - Vaccines, 2022 - mdpi.com
Cancer is a chronic disease, and it can be lethal due to limited therapeutic options. The
conventional treatment options for cancer have numerous challenges, such as a low blood …

Lipid nanoparticle-based mRNA delivery systems for cancer immunotherapy

J Han, J Lim, CPJ Wang, JH Han, HE Shin, SN Kim… - Nano …, 2023 - Springer
Cancer immunotherapy, which harnesses the power of the immune system, has shown
immense promise in the fight against malignancies. Messenger RNA (mRNA) stands as a …

The importance of cellular metabolic pathways in pathogenesis and selective treatments of hematological malignancies

M Soltani, Y Zhao, Z Xia, M Ganjalikhani Hakemi… - Frontiers in …, 2021 - frontiersin.org
Despite recent advancements in the treatment of hematologic malignancies and the
emergence of newer and more sophisticated therapeutic approaches such as …

Emergence of mRNA vaccines in the management of cancer

MI Mohamad Razif, N Nizar… - Expert Review of …, 2023 - Taylor & Francis
Introduction mRNA vaccines have been developed as a promising cancer management. It is
noted that specification of the antigen sequence of the target antigen is necessary for the …

Unveiling the immune microenvironment's role in breast cancer: A glimpse into promising frontiers

A Kotsifaki, N Alevizopoulos, V Dimopoulou… - International Journal of …, 2023 - mdpi.com
Breast cancer (BC), one of the most widespread and devastating diseases affecting women
worldwide, presents a significant public health challenge. This review explores the emerging …