Cis-and trans-acting expression quantitative trait loci differentially regulate gamma-globin gene expression

EM Shaikho, JJ Farrell, DHK Chui, P Sebastiani… - BioRxiv, 2018 - biorxiv.org
Genetic association studies have detected two trans-acting quantitative trait loci (QTL) on
chromosomes 2, 6 and one cis-acting QTL on chromosome 11 that were associated with …

Investigating cis-and trans-Acting Elements Involved in Regulating Fetal Hemoglobin Gene Expression Using High Throughput Genetic Data

ESE Mohammed - 2018 - search.proquest.com
Sickle cell anemia is caused by a single mutation in the?-hemoglobin gene, HBB. The
disease originated in Africa and affects millions of people worldwide. Sickle hemoglobin …

Investigating cis-and trans-acting elements involved in regulating fetal hemoglobin gene expression using high throughput genetic data

E Shaikho Elhaj Mohammed - 2018 - open.bu.edu
Sickle cell anemia is caused by a single mutation in the β-hemoglobin gene, HBB. The
disease originated in Africa and affects millions of people worldwide. Sickle hemoglobin …