Natural medicinal compounds target signal transduction pathways to overcome ABC drug efflux transporter-mediated multidrug resistance in cancer
ATP-binding cassette (ABC) transporters such as ABCB1, ABCG2, and ABCC1 are the
major players in drug efflux-mediated multidrug resistance (MDR), which severely affects the …
major players in drug efflux-mediated multidrug resistance (MDR), which severely affects the …
Next-generation hydrogels as biomaterials for biomedical applications: exploring the role of curcumin
VS Madamsetty, M Vazifehdoost, SH Alhashemi… - ACS …, 2023 - ACS Publications
Since the first report on the pharmacological activity of curcumin in 1949, enormous amounts
of research have reported diverse activities for this natural polyphenol found in the dietary …
of research have reported diverse activities for this natural polyphenol found in the dietary …
Unveiling autophagy complexity in leukemia: The molecular landscape and possible interactions with apoptosis and ferroptosis
YY Jung, KS Ahn, M Shen - Cancer Letters, 2024 - Elsevier
Autophagy is a self-digestion multistep process in which causes the homeostasis through
degradation of macromolecules and damaged organelles. The autophagy-mediated tumor …
degradation of macromolecules and damaged organelles. The autophagy-mediated tumor …
Improved Cytotoxicity and Induced Apoptosis in HeLa Cells by Co‐loading Vitamin E Succinate and Curcumin in Nano‐MIL‐88B‐NH2
RK Alavijeh, K Akhbari - ChemBioChem, 2023 - Wiley Online Library
One of the strategies for improved therapeutic effects in cancer therapy is combination
chemotherapy. In this study, a flexible nano‐MOF (Fe‐MIL‐88B‐NH2) was synthesized in a …
chemotherapy. In this study, a flexible nano‐MOF (Fe‐MIL‐88B‐NH2) was synthesized in a …
Curcumin: a bioactive compound with molecular targets for human malignancies
Cancer is the second leading cause of death in the world and one of the major public health
problems. Curcumin has anticancer activity including inducing apoptosis and inhibiting …
problems. Curcumin has anticancer activity including inducing apoptosis and inhibiting …
[PDF][PDF] Journal of Population Therapeutics & Clinical Pharmacology
F Mehmood, UE Toktobolotovich, HM Arsalan… - researchgate.net
Background: Chronic myeloid leukemia (CML) is being a disorder marked by excessive
proliferation of bone marrow elements and especially blood cells (leucocytes). Structural …
proliferation of bone marrow elements and especially blood cells (leucocytes). Structural …