Diagnosis of cerebral amyloid angiopathy: evolution of the Boston criteria

SM Greenberg, A Charidimou - Stroke, 2018 - Am Heart Assoc
492 Stroke February 2018 lobar hemorrhages required for probable CAA, or alternatively
preclude probable CAA if in deep territories. The rationale for counting all types of …

Vascular cognitive impairment

M Dichgans, D Leys - Circulation research, 2017 - Am Heart Assoc
Cerebrovascular disease typically manifests with stroke, cognitive impairment, or both.
Vascular cognitive impairment refers to all forms of cognitive disorder associated with …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022 - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

Emerging concepts in sporadic cerebral amyloid angiopathy

A Charidimou, G Boulouis, ME Gurol, C Ayata… - Brain, 2017 - academic.oup.com
Sporadic cerebral amyloid angiopathy is a common, well-defined small vessel disease and
a largely untreatable cause of intracerebral haemorrhage and contributor to age-related …

Understanding the role of the perivascular space in cerebral small vessel disease

R Brown, H Benveniste, SE Black… - Cardiovascular …, 2018 - academic.oup.com
Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions

A Charidimou, J Linn, MW Vernooij, C Opherk… - Brain, 2015 - academic.oup.com
Cortical superficial siderosis describes a distinct pattern of blood-breakdown product
deposition limited to cortical sulci over the convexities of the cerebral hemispheres, sparing …

MRI-visible perivascular spaces in cerebral amyloid angiopathy and hypertensive arteriopathy

A Charidimou, G Boulouis, M Pasi, E Auriel… - Neurology, 2017 - AAN Enterprises
Objective: To assess MRI-visible enlarged perivascular spaces (EPVS) burden and different
topographical patterns (in the centrum semiovale [CSO] and basal ganglia [BG]) in 2 …

MRI-visible perivascular space location is associated with Alzheimer's disease independently of amyloid burden

G Banerjee, HJ Kim, Z Fox, HR Jäger, D Wilson… - Brain, 2017 - academic.oup.com
Perivascular spaces that are visible on magnetic resonance imaging (MRI) are a
neuroimaging marker of cerebral small vessel disease. Their location may relate to the type …

Perivascular spaces and their associations with risk factors, clinical disorders and neuroimaging features: a systematic review and meta-analysis

F Francis, L Ballerini… - International Journal of …, 2019 - journals.sagepub.com
Background Perivascular spaces, visible on brain magnetic resonance imaging, are thought
to be associated with small vessel disease, neuroinflammation, and to be important for …

Total small vessel disease score and risk of recurrent stroke: validation in 2 large cohorts

KK Lau, L Li, U Schulz, M Simoni, KH Chan, SL Ho… - Neurology, 2017 - AAN Enterprises
Objective: In patients with TIA and ischemic stroke, we validated the total small vessel
disease (SVD) score by determining its prognostic value for recurrent stroke. Methods: Two …