Lung cancer is the leading cause of cancer-related mortality. While the majority of lung
cancers are associated with tobacco smoke, approximately 10–15% of US lung cancers …

Acquired drug resistance is a major factor limiting the effectiveness of targeted cancer
therapies. Targeting tumors with kinase inhibitors induces complex adaptive programs that …

Lung cancer progresses without obvious symptoms and is detected in most patients at late
stages, causing a high rate of mortality. Avocado peels (AVP) were thought to be biowaste …

With the use of high-resolution chest imaging system and lung cancer screening program,
patients with multiple primary lung cancers (MPLCs) are becoming a growing population in …

Background Accumulating evidence suggests that dysregulated snoRNA may play a role in
the development of malignancy. In the present study, we investigated the role of SNORD78 …

Introduction LY2603618 is a selective inhibitor of checkpoint kinase 1 (CHK1) protein
kinase, a key regulator of the DNA damage checkpoint, and is predicted to enhance the …

Despite recent advances in the management of non-small cell lung cancer (NSCLC), the
prognosis of NSCLC is still relatively poor. Thus, it is of great importance to identify novel …

Aims The aim of this study was to evaluate the prevalence of PBK/TOPK (PDZ‐binding
kinase/T‐LAK cell‐originated protein kinase) expression, and explore the prognostic …

Non-small cell lung cancer (NSCLC) is the major cause of cancer death worldwide.
Increasing evidences show that long non coding RNAs (lncRNAs) are widely involved in the …

JAK1 and JAK3 are recurrently mutated in acute lymphoblastic leukemia. These tyrosine
kinases associate with heterodimeric cytokine receptors such as IL-7 receptor or IL-9 …