The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Background Severe coronavirus disease 2019 (COVID-19) can manifest in rapid
decompensation and respiratory failure with elevated inflammatory markers, consistent with …

Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

Abstract The World Health Organization (WHO) declared COVID-19 (novel coronavirus) as a
global pandemic in the middle of March 2020, after the disease spread to more than 150 …

Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …

Using AI, we identified baricitinib as having antiviral and anticytokine efficacy. We now show
a 71%(95% CI 0.15 to 0.58) mortality benefit in 83 patients with moderate-severe SARS-CoV …

Background The multimorbid burden and use of systemic immunosuppressants in people
with psoriasis may confer greater risk of adverse outcomes of coronavirus disease 2019 …

COVID‐19 is highly contagious pathogenic viral infection initiated from Wuhan seafood
wholesale market of China on December 2019 and spread rapidly around the whole world …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …