The guideline is intended for use by healthcare providers who care for adult and pediatric
patients with group A streptococcal pharyngitis. The guideline updates the 2002 Infectious …

OBJECTIVE: To conduct a systematic review to determine whether clinical findings can be
used to rule in or to rule out streptococcal pharyngitis in children. STUDY DESIGN: Two …

OBJECTIVES: Prevalence estimates can help clinicians make informed decisions regarding
diagnostic testing of children who present with symptoms of pharyngitis. We conducted a …

Common signs and symptoms of streptococcal pharyngitis include sore throat, temperature
greater than 100.4° F (38° C), tonsillar exudates, and cervical adenopathy. Cough, coryza …

BACKGROUND AND OBJECTIVES: Antimicrobials are frequently prescribed for acute
respiratory tract infections (ARTI), although many are viral. We aimed to determine bacterial …

Group A beta-hemolytic streptococcal (GABHS) infection causes 15% to 30% of sore throats
in children and 5% to 15% in adults, and is more common in the late winter and early spring …

CONTEXT: The degree to which clinical prediction rules (CPRs) for children meet published
standards is unclear. OBJECTIVE: To systematically review the quality, performance, and …

Background—Acute rheumatic fever and subsequent rheumatic heart disease remain
significant in developing countries. We describe a cost-effective analysis of 7 strategies for …

Background Rheumatic heart disease (RHD) is a chronic cardiac condition with an
infectious aetiology, causing high disease burden in low-income settings. Affected …

We now stand at a critical juncture for rheumatic fever (RF) and rheumatic heart disease
(RHD) control. In recent years, we have seen a surge of interest in these diseases in regions …