Monkeypox virus host factor screen using haploid cells identifies essential role of GARP complex in extracellular virus formation

S Realegeno, AS Puschnik, A Kumar… - Journal of …, 2017 - Am Soc Microbiol
Monkeypox virus (MPXV) is a human pathogen that is a member of the Orthopoxvirus genus,
which includes Vaccinia virus and Variola virus (the causative agent of smallpox). Human …

Characterization of a novel galactose β1,3-N-acetylglucosaminyltransferase (β3Gn-T8): the complex formation of β3Gn-T2 and β3Gn-T8 enhances enzymatic activity

A Seko, K Yamashita - Glycobiology, 2005 - academic.oup.com
We characterized a novel member of the β1, 3-N-acetylglucosaminyltransferase (β3Gn-T)
gene family, β3Gn-T8. A recombinant soluble form of β3Gn-T8 was expressed in Pichia …

Knockdown of β3GnT8 reverses 5‑fluorouracil resistance in human colorectal cancer cells via inhibition the biosynthesis of polylactosamine‑type N‑glycans

L Shen, M Yu, X Xu, L Gao, J Ni… - … journal of oncology, 2014 - spandidos-publications.com
Aberrant glycosylation is known to be associated with cancer chemoresistance. β‑1, 3‑N‑
acetylglucosaminyltransferase (β3GnT) 8, which synthesizes polylactosamine on β1‑6 …

A phylogenetic view and functional annotation of the animal β1, 3-glycosyltransferases of the GT31 CAZy family

D Petit, RE Teppa, A Harduin-Lepers - Glycobiology, 2021 - academic.oup.com
Abstract The formation of β1, 3-linkages on animal glycoconjugates is catalyzed by a subset
of β1, 3-glycosyltransferases grouped in the Carbohydrate-Active enZYmes family …

Comprehensive prognostic and immune analysis of a glycosylation related risk model in pancreatic cancer

XA Liu, J Shi, L Tian, B Xiao, K Zhang, Y Zhu, YF Zhang… - BMC cancer, 2023 - Springer
Background Pancreatic cancer (PC) is a malignant tumor with extremely poor prognosis,
exhibiting resistance to chemotherapy and immunotherapy. Nowadays, it is ranked as the …

High expression of β3GnT8 is associated with the metastatic potential of human glioma

J Liu, L Shen, L Yang, S Hu… - … journal of molecular …, 2014 - spandidos-publications.com
Abstract Changes in glycosylation due to specific alterations of glycosyltransferase activity
have been shown in various tumor cells, including human glioma cells. β1, 3-N …

β3GnT8 regulates the metastatic potential of colorectal carcinoma cells by altering the glycosylation of CD147

J Ni, Z Jiang, L Shen, L Gao, M Yu… - Oncology …, 2014 - spandidos-publications.com
Aberrant glycosylation of cell surface glycoproteins is commonly associated with the
invasion and metastasis of colorectal carcinomas, which can be attributed to the upregulated …

β3GnT8 promotes colorectal cancer cells invasion via CD147/MMP2/Galectin3 axis

Z Jiang, H Zhang, C Liu, J Yin, S Tong, J Lv… - Frontiers in …, 2018 - frontiersin.org
β1, 3-N-acetylglucosaminyltransferase (β3GnT8) and β3GnT2 are key enzymes that
catalyzes the formation of polylactosamine glycan structures by transferring GlcNAc to tetra …

β3GnT8 plays an important role in CD147 signal transduction as an upstream modulator of MMP production in tumor cells

Z Jiang, S Hu, D Hua, J Ni, L Xu, Y Ge… - Oncology …, 2014 - spandidos-publications.com
Aberrant carbohydration by related glycosyltransferases plays an important role in the
progression of cancer. This study focused on the ablity of β-1, 3-N …

[PDF][PDF] Isolation and characterization of novel human short-chain dehydrogenase/reductase SCDR10B which is highly expressed in the brain and acts as …

C Huang, B Wan, B Gao, S Hexige… - Acta Biochimica …, 2009 - bibliotekanauki.pl
Hydroxysteroid dehydrogenase belongs to the subfamily of short-chain dehydrogenases/
reductases (SDR), and 11-β-hydroxysteroid dehydrogenase catalyzes the interconversion of …