Monkeypox virus in Nigeria: infection biology, epidemiology, and evolution
E Alakunle, U Moens, G Nchinda, MI Okeke - Viruses, 2020 - mdpi.com
Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of
orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of …
orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state) after 39 years of …
The roles of histone deacetylases and their inhibitors in cancer therapy
G Li, Y Tian, WG Zhu - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Genetic mutations and abnormal gene regulation are key mechanisms underlying
tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores …
tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores …
Poxvirus immune evasion
B Hernaez, A Alcamí - Annual Review of Immunology, 2024 - annualreviews.org
Poxviruses have evolved a wide array of mechanisms to evade the immune response, and
we provide an overview of the different immunomodulatory strategies. Poxviruses prevent …
we provide an overview of the different immunomodulatory strategies. Poxviruses prevent …
Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection
Modified vaccinia Ankara (MVA) virus does not replicate in human cells and is the vaccine
deployed to curb the current outbreak of mpox. Here, we conduct a multiplexed proteomic …
deployed to curb the current outbreak of mpox. Here, we conduct a multiplexed proteomic …
Mpox virus and its ocular surface manifestations
The Mpox virus (MPXV) is the causative agent of human Mpox disease–a debilitating rash
illness similar to smallpox. Although Clade I MPXV has remained endemic to West and …
illness similar to smallpox. Although Clade I MPXV has remained endemic to West and …
[HTML][HTML] The monkeypox virus-host interplays
XM Yi, YL Lei, M Li, Z Li, S Li - Cell insight, 2024 - Elsevier
Monkeypox virus (MPXV) is a DNA virus belonging to the Orthopoxvirus genus within the
Poxviridae family which can cause a zoonotic infection. The unexpected non-endemic …
Poxviridae family which can cause a zoonotic infection. The unexpected non-endemic …
The main protease of SARS-CoV-2 cleaves histone deacetylases and DCP1A, attenuating the immune defense of the interferon-stimulated genes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus
disease 2019, constitutes an emerging human pathogen of zoonotic origin. A critical role in …
disease 2019, constitutes an emerging human pathogen of zoonotic origin. A critical role in …
HDAC4 in cancer: A multitasking platform to drive not only epigenetic modifications
E Cuttini, C Goi, E Pellarin, R Vida… - Frontiers in molecular …, 2023 - frontiersin.org
Controlling access to genomic information and maintaining its stability are key aspects of
cell life. Histone acetylation is a reversible epigenetic modification that allows access to DNA …
cell life. Histone acetylation is a reversible epigenetic modification that allows access to DNA …
Histone deacetylase 2 knockout suppresses immune escape of triple-negative breast cancer cells via downregulating PD-L1 expression
The PD-L1 overexpression is an important event of immune escape and metastasis in triple-
negative breast cancer (TNBC), but the molecular mechanism remains to be determined …
negative breast cancer (TNBC), but the molecular mechanism remains to be determined …
Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription
L Yang, S Chen, Q Zhao, C Pan, L Peng, Y Han, L Li… - Cell Reports, 2022 - cell.com
It is well known that interferon (IFN)-α/-β activates the JAK/STAT signaling pathway and
suppresses viral replication through the induction of IFN stimulated genes (ISGs). Here, we …
suppresses viral replication through the induction of IFN stimulated genes (ISGs). Here, we …