CRISPR/Cas9 technology has become the most examined gene editing technology in
recent years due to its simple design, yet low cost, high efficiency, and simple operation …

Gene knockout is a widely used method in biology for investigating gene function. Several
technologies are available for gene knockout, including zinc-finger nuclease technology …

Alzheimer's disease (AD) is the most common cause of dementia, with no current cure.
Consequently, alternative approaches focusing on early pathological events in specific …

The effectiveness of CRISPR/Cas9-mediated genome editing experiments largely depends
on the guide RNA (gRNA) used by the CRISPR/Cas9 system for target recognition and …

Alzheimer's disease (AD) is a progressive and irreversible brain disorder, which can occur
either sporadically, due to a complex combination of environmental, genetic, and epigenetic …

Cotton has enormous economic potential providing high-quality protein, oil, and fibre. A
large increase in cotton output is necessary due to the world's changing climate and …

Bioinformatics has become an indispensable technology in molecular biology for genome
editing. In this review, we outline various bioinformatic techniques necessary for genome …

Introduction Chimeric antigen receptor-expressing T cells (CAR T cells) have revolutionized
cancer treatment, particularly in B cell malignancies. However, the use of autologous T cells …

The European Cooperation in Science and Technology (COST) is an intergovernmental
organization dedicated to funding and coordinating scientific and technological research in …

Abstract Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas
nucleases and human induced pluripotent stem cell (iPSC) technology can reveal deep …