Self-driving laboratories for chemistry and materials science

G Tom, SP Schmid, SG Baird, Y Cao, K Darvish… - Chemical …, 2024 - ACS Publications
Self-driving laboratories (SDLs) promise an accelerated application of the scientific method.
Through the automation of experimental workflows, along with autonomous experimental …

A Pharma Perspective on Sustainability Advantages through adoption of Continuous Flow

LJ Nolan, SJ King, S Wharry, TS Moody… - Current Opinion in Green …, 2024 - Elsevier
The pharmaceutical sector is increasingly employing sustainable strategies to combat its
environmental impact through the implementation of green chemistry and engineering …

Hybrid Modeling of an Active Pharmaceutical Ingredient Flow Synthesis in a Ring-Opening Reaction of an Epoxide with a Grignard Reagent

J Kim, Y Hayashi, S Badr, K Okamoto… - Industrial & …, 2023 - ACS Publications
This work presents hybrid modeling of an active pharmaceutical ingredient flow synthesis in
a ring-opening reaction of an epoxide with a Grignard reagent. Conducting this reaction in a …

Total Synthesis of Dragocins A− C through Electrochemical Cyclization

BP Smith, NJ Truax, AS Pollatos… - Angewandte …, 2024 - Wiley Online Library
The first total synthesis of dragocins A− C, remarkable natural products containing an
unusual C4'oxidized ribose architecture bridged by a polyhydroxylated pyrrolidine, is …

Recent advances in photoredox catalytic transformations by using continuous-flow technology

X Yuan, HB Fan, J Liu, LZ Qin, J Wang, X Duan… - Chinese Journal of …, 2023 - Elsevier
Photoredox catalysis is regarded as an economically appealing method for highly efficient
and sustainable chemical syntheses. Nevertheless, numerous recent studies have revealed …

Practical synthesis of tetrahydrofolate by highly efficient catalytic hydrogenation in continuous flow

H Pang, J Huang, J Wang, G Wang, A Xu, L Luo… - Journal of Flow …, 2024 - Springer
Hundred-gram scale of highly selective catalytic hydrogenation of folic acid has been
developed, which is adopted continuous-flow technology with Raney Ni as a catalyst …

Constructing Time-varying and History-dependent Kinetic Models Via Reinforcement Learning

M Mowbray, EA Del Rio Chanona, D Zhang - 2023 - books.rsc.org
Mathematical modelling provides a significant contribution to the understanding and design
of chemical and biochemical reaction processes. For instance, for biochemical reaction …

Autonomous Synthesis and Self-optimizing Reactors

MJ Nieves-Remacha - 2023 - books.rsc.org
Traditional chemistry in laboratories has often been performed in conventional glass
reactors without an integrated automation system. However, manufacturing and pilot plants …

Microfluidic platform for screening the activity of immobilized photocatalysts for degradation of organic water pollutants

A Roibu, R Udroiu, A Dinu, L Andronic - 2024 - chemrxiv.org
Photochemistry screening platforms have the potential to accelerate the discovery and
development of new photocatalysts. This study presents the design and characterization of a …