The responses of patients to tumor therapies vary due to tumor heterogeneity. Tumor
stratification has been attracting increasing attention for accurately distinguishing between …

Atherosclerosis is a chronic inflammatory disease that leads to several acute cardiovascular
complications with poor prognosis. For decades, the role of the adventitial vasa vasorum …

Purpose: The aberrant expression of miR-221 is a hallmark of human cancers, including
hepatocellular carcinoma (HCC), and its involvement in drug resistance, together with a …

Objective BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)–specific
ultrasound molecular contrast agent (MCA), has shown promising results in multiple …

Ultrasound was developed several decades ago as a useful imaging modality, and it
became the second most popular diagnostic tool due to its non-invasiveness, real-time …

Ultrasound (US) imaging, due to its capabilities of real-time imaging, portability, low cost and
favorable safety, is frequently used as a diagnostic modality for the visualization of different …

Ultrasound contrast agents (UCAs) are used routinely in the clinic to enhance contrast in
ultrasonography. More recently, UCAs have been functionalised by conjugating ligands to …

Contrast-enhanced ultrasound (CEUS) is an emerging technology with no known
nephrotoxicity. CEUS has been utilized in cardiac and abdominal imaging for decades in …

Purpose Targeted nanobubbles can penetrate the tumor vasculature and achieve
ultrasound molecular imaging (USMI) of tumor parenchymal cells. However, most targeted …

Abstract A series of 1, 2, 3-triazole-containing Sorafenib analogues, in which the aryl urea
moiety of Sorafenib (1) was replaced with a 1, 2, 3-triazole ring linking a substituted phenoxy …