Impact of STING inflammatory signaling during intracellular bacterial infections

ES Guimarães, FV Marinho, NMGP de Queiroz… - Cells, 2021 - mdpi.com
The early detection of bacterial pathogens through immune sensors is an essential step in
innate immunity. STING (Stimulator of Interferon Genes) has emerged as a key mediator of …

[HTML][HTML] Lactobacillus acidophilus suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma through producing valeric acid

HCH Lau, X Zhang, F Ji, Y Lin, W Liang, Q Li… - …, 2024 - thelancet.com
Background Gut probiotic depletion is associated with non-alcoholic fatty liver disease-
associated hepatocellular carcinoma (NAFLD-HCC). Here, we investigated the prophylactic …

Effects of dietary rambutan (Nephelium lappaceum L.) peel powder on growth performance, immune response and immune-related gene expressions of striped catfish …

C Le Xuan, S Wannavijit, P Outama, N Montha… - Fish & Shellfish …, 2022 - Elsevier
This study aimed to evaluate the effects of rambutan peel powder (RP) on growth, skin
mucosal and serum immunities, and immune-related gene expression of striped catfish …

Interferons for Covid-19: A Literature Review on Their Therapeutic Potential, Clinical Data and Challenges

P Yadav, V Chandra, V Raghuvanshi, A Yadav… - 2023 - preprints.org
The 2019 COVID-19 pandemic caused by SARS-CoV-2 has resulted in many fatalities
worldwide. Despite various types of supportive care, mortality rates for patients with …

Burkholderia cepacia in cystic fibrosis children and adolescents: overall survival and immune alterations

G Shmarina, D Pukhalskaya, V Shmarin… - Frontiers in Cellular …, 2024 - frontiersin.org
Background In current literature there are only scarce data on the host inflammatory
response during Burkholderia cepacia complex (Bcc) persistence. The primary objective of …

A novel HOIP frameshift variant alleviates NF-kappaB signalling and sensitizes cells to TNF-induced death

M Wang, Y Bai, D Jiang, Y Wang, F Zhao… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Background HOIP is the catalytic subunit of the E3 ligase complex (linear ubiquitin chain
assembly complex), which is able to generate linear ubiquitin chains. However, the role of …

[PDF][PDF] Interferons as a Potential Therapeutic Drug for COVID-19: A Literature Review of Mechanisms, Current Clinical Trials, and Challenges

P Yadav, V Chandra… - JOURNAL OF …, 2023 - communitymedjournal.com
The 2019 COVID-19 pandemic caused by SARS-CoV-2 has resulted in many fatalities
worldwide. Despite various types of supportive care, mortality rates for patients with …

A Type VI Secretion System in Burkholderia Species cenocepacia and orbicola Triggers Distinct Macrophage Death Pathways Independent of the Pyrin …

NA Loeven, AD Reuven, AP McGee, C Dabi… - bioRxiv, 2023 - biorxiv.org
The Burkholderia cepacia complex contains opportunistic pathogens that cause chronic
infections and inflammation in lungs of people with cystic fibrosis. Two closely related …

Role of the Burkholderia cenocepacia Effector TecA in Pathogenesis During Lung Infection

N Loeven - 2022 - search.proquest.com
Burkholderia cenocepacia is a member of the Burkholderia cepacia complex (Bcc), a group
of bacteria with members responsible for causing lung infections in cystic fibrosis (CF) …

[PDF][PDF] A Novel HOIP Frameshift Variant Alleviates NF-kappaB Signaling and Sensitizes Cells to TNF-induced Death

X Tu, M Wang, Y Bai, D Jiang, Y Wang, Y Zhou, M Zhou… - 2023 - scholar.archive.org
The linear ubiquitin chain assembly complex (LUBAC) is the sole known complex that can
assemble linear ubiquitin chains. It is composed of three distinct subunits: HOIP, SHARPIN …