Development of multi-compartment 3d-printed tablets loaded with self-nanoemulsified formulations of various drugs: A new strategy for personalized medicine
This work aimed to develop a three-dimensional printed (3DP) tablet containing glimepiride
(GLMP) and/or rosuvastatin (RSV) for treatment of dyslipidemia in patients with diabetes …
(GLMP) and/or rosuvastatin (RSV) for treatment of dyslipidemia in patients with diabetes …
Development of 3D-printed, liquisolid and directly compressed glimepiride tablets, loaded with black seed oil self-nanoemulsifying drug delivery system: in vitro and in …
Glimepiride is characterized by an inconsistent dissolution and absorption profile due to its
limited aqueous solubility. The aim of this study was to develop glimepiride tablets using …
limited aqueous solubility. The aim of this study was to develop glimepiride tablets using …
Spreadsheet-based nonlinear analysis of in vitro release properties of a model drug from colloidal carriers
Abstract Analysis of in vitro dissolution profiles of encapsulated drugs usually involves the
linearization of the applied mathematical model and sometimes transformation of the …
linearization of the applied mathematical model and sometimes transformation of the …
Enhancement of simvastatin ex vivo permeation from mucoadhesive buccal films loaded with dual drug release carriers
TA Ahmed, AO Bawazir, WS Alharbi… - International Journal of …, 2020 - Taylor & Francis
Background Simvastatin (SMV), a hypocholesterolemic agent, suffers from very low
bioavailability due to its poor aqueous solubility and extensive first-pass metabolism …
bioavailability due to its poor aqueous solubility and extensive first-pass metabolism …
Highly soluble glimepiride and irbesartan co-amorphous formulation with potential application in combination therapy
One-third of the population of the USA suffers from metabolic syndrome (MetS). Treatment of
patients with MetS regularly includes drugs prescribed simultaneously to treat diabetes and …
patients with MetS regularly includes drugs prescribed simultaneously to treat diabetes and …
Formulation and clinical investigation of optimized vinpocetine lyoplant-tabs: new strategy in development of buccal solid dosage form
TA Ahmed - Drug design, development and therapy, 2018 - Taylor & Francis
Background This work aimed to develop a new solid dosage formulation of vinpocetine
(VPN) in the form of buccal freeze-dried pullulan-based tablets (lyoplant-tabs) loaded with …
(VPN) in the form of buccal freeze-dried pullulan-based tablets (lyoplant-tabs) loaded with …
Enhancing the Hypolipidemic Effect of Simvastatin in Poloxamer-Induced Hyperlipidemic Rats via Liquisolid Approach: Pharmacokinetic and Pharmacodynamic …
This study aimed to enhance the dissolution of simvastatin (SMV) through its formulation in
liquisolid tablets (LSTs) to improve its bioavailability and hypolipidemic activity after oral …
liquisolid tablets (LSTs) to improve its bioavailability and hypolipidemic activity after oral …
[HTML][HTML] Controlled release of bilayer tablet comprising vitamin B6 rapid-release layer and melatonin sustained-release layer
Y Wang, J Xu, N Gao, H Lv, M Sun, P Zhang - Pharmaceutical Science …, 2023 - Elsevier
Here, the formulation of a novel bilayer tablet comprising a vitamin B 6 rapid-release layer
and a melatonin sustained-release layer is described. The effects of viscosity and …
and a melatonin sustained-release layer is described. The effects of viscosity and …
The Clinical Pharmacokinetics and Pharmacodynamics of Glimepiride—A Systematic Review and Meta-Analysis
Background/Objectives: Glimepiride (GLM), a commonly used sulphonylurea drug for the
management of type 2 diabetes mellitus (T2DM), has been the subject of numerous studies …
management of type 2 diabetes mellitus (T2DM), has been the subject of numerous studies …
Solubilization study of antihypertensive drug Irbesartan in EO-PO based polymeric nanomicelle and optimization of its release behavior
Irbesartan (IRB) has low bioavailability due to its poor aqueous solubility and dissolution
rate, thereby making it imperative to understand their absorption behavior. The present …
rate, thereby making it imperative to understand their absorption behavior. The present …