Sleep is a fundamental requirement of life and is integral to health. Deviation from optimal
sleep associates with numerous diseases including those of the cardiovascular system …

A workshop titled “Beyond the Symptom: The Biology of Fatigue” was held virtually
September 27–28, 2021. It was jointly organized by the Sleep Research Society and the …

Sleep is a vital and evolutionarily conserved process, critical to daily functioning and
homeostatic balance. Losing sleep is inherently stressful and leads to numerous detrimental …

Background Sleep disturbances, as manifested in insomnia symptoms of difficulties falling
asleep or frequent nighttime awakenings, are a strong risk factor for a diverse range of …

Background Sleep deficiencies, such as manifested in short sleep duration or insomnia
symptoms, are known to increase the risk for multiple disease conditions involving …

Abstract Study Objectives There is strong evidence that sleep disturbances are an
independent risk factor for the development of chronic pain conditions. The mechanisms …

A circadian disruption, manifested by disturbed sleep and low-grade inflammation, is
commonly seen in cardiovascular diseases (CVDs). The decline in plasma melatonin, which …

Sleep strongly supports the formation of adaptive immunity, eg, after vaccination. However,
the underlying mechanisms remain largely obscure. Here we show in healthy humans that …

Introduction Sleep is an important neurophysiological condition that is intricately linked to
general health, laying the basis for both physiological and psychological well‐being. A …

Abstract Study Objectives Although poor sleep quality is associated with lower CD4+ T cell
counts among people living with HIV (PLWH), the association between objective sleep …