Biopolymers based aerogels: A review on revolutionary solutions for smart therapeutics delivery

HPSA Khalil, EB Yahya, F Jummaat, AS Adnan… - Progress in Materials …, 2023 - Elsevier
Biopolymers-based aerogels have gained the attention of many scientists in medical and
pharmaceutical applications. Biopolymers-based aerogels are utilized extensively in the …

The ascension of nanosponges as a drug delivery carrier: preparation, characterization, and applications

K Tiwari, S Bhattacharya - Journal of Materials Science: Materials in …, 2022 - Springer
Nanosponges are nanosized drug carriers with a three-dimensional structure created by
crosslinking polymers. They have the advantage of being able to hold a wide range of drugs …

Light-Sensitive Lactococcus lactis for Microbe–Gut–Brain Axis Regulating via Upconversion Optogenetic Micro-Nano System

H Pan, T Sun, M Cui, N Ma, C Yang, J Liu, G Pang… - ACS …, 2022 - ACS Publications
The discovery of the gut–brain axis has proven that brain functions can be affected by the
gut microbiota's metabolites, so there are significant opportunities to explore new tools to …

Microencapsulation for pharmaceutical applications: a review

C Yan, SR Kim - ACS Applied Bio Materials, 2024 - ACS Publications
In order to improve bioavailability, stability, control release, and target delivery of active
pharmaceutical ingredients (APIs), as well as to mask their bitter taste, to increase their …

Application of non-viral vectors in drug delivery and gene therapy

S Ren, M Wang, C Wang, Y Wang, C Sun, Z Zeng… - Polymers, 2021 - mdpi.com
Vectors and carriers play an indispensable role in gene therapy and drug delivery. Non-viral
vectors are widely developed and applied in clinical practice due to their low …

Pharmaceutical characterization of probucol bile acid–lithocholic acid nanoparticles to prevent chronic hearing related and similar cellular oxidative stress pathologies

SR Wagle, CM Ionescu, B Kovacevic, M Jones… - …, 2023 - Taylor & Francis
Background: Sensorineural hearing loss has been associated with oxidative stress.
However, an antioxidant that passes effectively through the ear remains elusive. Method …

Novel nanoencapsulation technology and its potential role in bile acid‐based targeted gene delivery to the inner ear

T Foster, M Lewkowicz, C Quintas, CM Ionescu… - Small, 2023 - Wiley Online Library
Hearing loss impacts a large proportion of the global population. Damage to the inner ear, in
particular the sensitive hair cells, can impact individuals for the rest of their lives. There are …

A review on recent advancement on age-related hearing loss: the applications of nanotechnology, drug pharmacology, and biotechnology

J Chester, E Johnston, D Walker, M Jones, CM Ionescu… - Pharmaceutics, 2021 - mdpi.com
Aging is considered a contributing factor to many diseases such as cardiovascular disease,
Alzheimer's disease, and hearing loss. Age-related hearing loss, also termed presbycusis, is …

Novel hydrogel comprising non-ionic copolymer with various concentrations of pharmacologically active bile acids for cellular injectable gel

B Kovacevic, SR Wagle, CM Ionescu, M Jones… - Colloids and Surfaces B …, 2023 - Elsevier
Deoxycholic acid (DCA) is a bile acid capable of forming micelles and modifying the
properties of hydrogels. We incorporated DCA in sodium alginate (SA) and poloxamer 407 …

Probucol-bile acid nanoparticles: A Novel Approach and Promising Solution to Prevent Cellular Oxidative Stress in Sensorineural Hearing Loss.

SR Wagle, B Kovacevic, T Foster… - Journal of Drug …, 2024 - Taylor & Francis
The use of anti-oxidants could thus prove an effective medication to prevent or facilitate
recovery from oxidative stress-induced sensorineural hearing loss (SNHL). One promising …