Ischemic stroke is a devastating brain injury resulting in high mortality and substantial loss of
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …

Women appear to be more vulnerable to the depressogenic effects of inflammation than
men. Chronic stress, one of the most pertinent risk factors of depression and anxiety, is …

The activation of resident microglial cells, alongside the infiltration of peripheral
macrophages, are key neuroinflammatory responses to traumatic brain injury (TBI) that are …

Background The necessity of including both males and females in molecular neuroscience
research is now well understood. However, there is relatively limited basic biological data on …

Aim From birth to old age, males generally have poorer disease outcomes compared to
females. Preterm infants display a marked gender disparity in disease outcomes, and the …

The epilepsies are common neurologic disorders characterized by spontaneous recurrent
seizures. Boys, girls, men, and women of all ages are affected by epilepsy and, in many …

Perinatal brain injury is the leading cause of neurological mortality and morbidity in
childhood ranging from motor and cognitive impairment to behavioural and neuropsychiatric …

Stroke is not only a leading cause of mortality and morbidity worldwide it also
disproportionally affects women. There are currently over 500,000 more women stroke …

Objective To assess the effect of serine protein inhibitor A3N (serpinA3N) in ischemic stroke
and to explore its mechanism of action. Methods Mouse ischemic stroke model was induced …

Cohort studies have demonstrated a higher vulnerability in males towards ischemic and/or
hypoxic-ischemic injury in infants born near-or full-term. Male sex was also associated with …