Staphylococcus aureus is recognized as commensal as well as opportunistic pathogen of
humans and animals. Methicillin resistant strain of S. aureus (MRSA) has emerged as a …

The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Comprehensive profiling of lipid species in a biological sample, or lipidomics, is a valuable
approach to elucidating disease pathogenesis and identifying biomarkers. Currently, a …

Objectives Dalbavancin is a lipoglycopeptide active against methicillin-resistant
Staphylococcus aureus (MRSA). Its long half-life (8.5–16 days) allows for once-weekly or …

The global threat of numerous infectious diseases creates a great need to develop new
diagnostic methods to facilitate the appropriate prescription of antimicrobial therapy. More …

The swift rise of antibiotic resistance, coupled with limited new antibiotic discovery, presents
a significant hurdle to global public health, demanding innovative therapeutic solutions …

The lipid membrane is gaining appreciation as a critical factor in the emergence of antibiotic
resistance, both for antibiotics that target lipid synthesis or the membrane directly and for cell …

The popularity of mass spectrometry–based lipidomics has soared in the past decade. While
the majority of the lipidomics work is being performed in mammalian and other eukaryotic …

Vancomycin and daptomycin are first-line drugs for the treatment of complicated methicillin-
resistant Staphylococcus aureus (MRSA) infections, including bacteremia. However, their …