Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …

Atopic dermatitis (AD) is a public health concern and is increasing in prevalence in urban
areas. Recent advances in sequencing technology have demonstrated that the development …

The epidermis forms a barrier that defends the body from desiccation and entry of harmful
substances, while also sensing and integrating environmental signals. The tightly …

Gut microbial disturbance affects allergic diseases including asthma, atopic dermatitis (AD)
via the aberrant immune response. Some Bifidobacterial species and strains have been …

Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

The gut microbiota has a crucial effect on regulating the intestinal mucosal immunity and
maintaining intestinal homeostasis both in health and in disease state. Many effects are …

Skin cancer is the most common type of cancer in the US with an increasing prevalence
worldwide. While ultraviolet (UV) radiation is a well-known risk factor, there is emerging …

Despite recent advances in understanding microbial diversity in skin homeostasis, the
relevance of microbial dysbiosis in inflammatory disease is poorly understood. Here we …

T helper-17 (Th17) cells, which mainly produce IL-17, are associated with development of
various autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases …