Targeting the tumour vasculature: from vessel destruction to promotion
S Guelfi, K Hodivala-Dilke, G Bergers - Nature Reviews Cancer, 2024 - nature.com
As angiogenesis was recognized as a core hallmark of cancer growth and survival, several
strategies have been implemented to target the tumour vasculature. Yet to date, attempts …
strategies have been implemented to target the tumour vasculature. Yet to date, attempts …
The balance of STING signaling orchestrates immunity in cancer
KRB Lanng, EL Lauridsen, MR Jakobsen - Nature Immunology, 2024 - nature.com
Over the past decade, it has become clear that the stimulator of interferon genes (STING)
pathway is critical for a variety of immune responses. This endoplasmic reticulum-anchored …
pathway is critical for a variety of immune responses. This endoplasmic reticulum-anchored …
Agonists and Inhibitors of the cGAS-STING Pathway
X Yu, L Cai, J Yao, C Li, X Wang - Molecules, 2024 - mdpi.com
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is
pivotal in immunotherapy. Several agonists and inhibitors of the cGAS-STING pathway have …
pivotal in immunotherapy. Several agonists and inhibitors of the cGAS-STING pathway have …
AIM2 promotes excitatory glutamate receptor expression by inhibiting STING and contributes to bone cancer pain in male mice
L Wang, X Xu, S Su, B Li, K Zhang, X Yu, Y Xiao… - Scientific Reports, 2024 - nature.com
Bone cancer pain (BCP) is a common clinical problem in cancer patients. The plasticity of
excitatory neurons within the spinal dorsal horn plays a significant role in the development of …
excitatory neurons within the spinal dorsal horn plays a significant role in the development of …
The role of cGAS-STING signaling in the development and therapy of head and neck squamous cell carcinoma
C Shao, J Chen, B Qiang, J Ye, F Yan… - Frontiers in …, 2024 - frontiersin.org
The cGAS-STING signaling pathway plays a critical role in innate immunity and defense
against viral infections by orchestrating intracellular and adaptive immune responses to …
against viral infections by orchestrating intracellular and adaptive immune responses to …
Roles of Water Molecules in STING Activation: A Computational Perspective
H Gates, R Payne, H Pfeifer, L Le, S Crivelli… - 2024 - chemrxiv.org
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is
crucial in the innate immune response, particularly in cancer immunotherapy. Despite …
crucial in the innate immune response, particularly in cancer immunotherapy. Despite …
[PDF][PDF] Differential regulation of the STING pathway in HPV+ and HPV-head and neck cancers
E Saulters - 2024 - livrepository.liverpool.ac.uk
Differential regulation of the STING pathway in HPV+ and HPV- head and neck cancers Page
1 Differential regulation of the STING pathway in HPV+ and HPV- head and neck cancers …
1 Differential regulation of the STING pathway in HPV+ and HPV- head and neck cancers …