[HTML][HTML] Targeting hypoxia-inducible factor-1alpha: A new strategy for triple-negative breast cancer therapy

Q Liu, C Guan, C Liu, H Li, J Wu, C Sun - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …

[HTML][HTML] The potential role and status of IL-17 family cytokines in breast cancer

X Song, C Wei, X Li - International immunopharmacology, 2021 - Elsevier
Breast cancer (BC) is currently the most common malignant tumor of women in the world. At
present, the development of BC is accelerating and showing a younger trend, which may be …

COVID-19. Pandemic surgery guidance

BLDM Brücher, G Nigri, A Tinelli, J Florencio… - 4 OPEN, 2020 - iris.uniroma1.it
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …

Research progress on molecular subtyping and modern treatment of triple-negative breast cancer

L Tong, X Yu, S Wang, L Chen, Y Wu - Breast Cancer: Targets and …, 2023 - Taylor & Francis
Breast cancer has become the most common malignant tumor worldwide. Triple-negative
breast cancer (TNBC) is a type of breast cancer that is negative for estrogen receptor (ER) …

The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer

K Li, J Zhang, Y Tian, Y He, X Xu, W Pan, Y Gao… - Oncogene, 2020 - nature.com
Previous studies have shown that the main function of VASP is to regulate the cytoskeleton
and play an important role in promoting tumor cell metastasis. In this study, we first reveal …

Bioactive lipids in age-related disorders

UN Das - Reviews on new drug targets in age-related disorders, 2020 - Springer
Our own studies and those of others have shown that defects in essential fatty acid (EFA)
metabolism occurs in age-related disorders such as obesity, type 2 diabetes mellitus …

ITGA3 interacts with VASP to regulate stemness and epithelial-mesenchymal transition of breast cancer cells

H Zhang, X Cui, X Li, L Li - Gene, 2020 - Elsevier
Background The interaction of integrin and extracellular matrix (ECM) has a profound
implication on pathological conditions such as tumor growth and infiltration. Related reports …

Detecting vasodilation as potential diagnostic biomarker in breast cancer using deep learning-driven thermomics

B Yousefi, H Akbari, XPV Maldague - Biosensors, 2020 - mdpi.com
Breast cancer is the most common cancer in women. Early diagnosis improves outcome and
survival, which is the cornerstone of breast cancer treatment. Thermography has been …

IL‐17A promotes cell migration and invasion of glioblastoma cells via activation of PI 3K/AKT signalling pathway

Q Zheng, S Diao, Q Wang, C Zhu, X Sun… - Journal of cellular …, 2019 - Wiley Online Library
Glioblastomas (GBM s) are the most common of both benign and malignant primary brain
tumours, in which the inflammatory and immunologic abnormalities are involved. Interleukin …

ZC3H12A inhibits tumor growth and metastasis of breast cancer under hypoxic condition via the inactivation of IL-17 signaling pathway

Z Luo, F Yang, K Liu, Z Ding - Cell Cycle, 2024 - Taylor & Francis
Hypoxia is a major contributor to tumor microenvironment (TME) and metastasis in most
solid tumors. We seek to screen hypoxia-related genes affecting metastasis in breast cancer …