Chemotherapy resistance is one of the major challenges in cancer treatment, including
leukemia. A massive array of research is evaluating combinations of drugs directed against …

This review provides a comprehensive overview of the recent advancements in research on
ATF4 (Activating Transcription Factor 4) within the field of oncology. As a crucial transcription …

Chronic myeloid leukemia (CML) is a myeloproliferative haematological malignancy
characterized by constitutive activation of BCR-ABL1 tyrosine kinase in the majority of …

Endoplasmic reticulum (ER) stress is implicated in cardiac arrhythmia whereas the
associated mechanisms remain inadequately understood. Kv1. 5 channels are essential for …

Background/Aim: Metformin is a widely used drug for type 2 diabetes mellitus and has
recently attracted broad attention for its therapeutic effects on many cancers. This study …

Epidemiologic studies of diabetic patients treated with metformin identified significantly
lower incidences of cancer. From this, there is growing interest in the use of metformin to …

Esophageal squamous cell carcinoma (ESCC) showed limited treatment outcome and poor
prognosis. This study aimed to screen potential biomarkers and drugs in ESCC. Firstly …

Out of the all newly diagnosed lung cancers, non-small cell lung carcinoma (NSCLC)
comprises 80-85%. When treating advanced stages of the disease, conventional therapy …

Sažetak Nesitnoćelijski karcinom pluća (NSCLC) sačinjava 80-85% svih dijagnostikovanih
formi karcinoma pluća. Konvencionalni terapijski modaliteti pokazuju malu uspešnost u …

Out of the all newly diagnosed lung cancers, non-small cell lung carcinoma (NSCLC)
comprises 80-85%. When treating advanced stages of the disease, conventional therapy …